DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRMP and dpys

DIOPT Version :9

Sequence 1:	NP_730954.2	Gene:	CRMP / 40675	FlyBaseID:	FBgn0023023	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	XP_031760022.1	Gene:	dpys / 100491365	XenbaseID:	XB-GENE-959927	Length:	499	Species:	Xenopus tropicalis

Alignment Length:	500	Identity:	289/500 - (57%)
Similarity:	362/500 - (72%)	Gaps:	11/500 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHT 81
            ::::::.|:.|::||.|.||.||||||||:::.:|.:.....|.|::.|||.|.:::|||||.||
Frog     2 ASRSQILIQGGKVVNADCSFVADVYIEDGLVRDIGMNLRQAKPKGIKVIDAGGKLLLPGGIDTHT 66

  Fly    82 HMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHV 146
            |.|.||.|:.:||||..||||||||||||:|||.:|.|.||:||||:.|||||||||||||.|||
Frog    67 HFQFPFMGSQSVDDFSQGTKAAVAGGTTMVIDFAIPKKGESLIEAYETWRSWADPKVCCDYSLHV 131

  Fly   147 GITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDI 211
            .:||||..|.||:|||.::.||||||.|||||.||.:||.:|...|...:.:..:|.|||||||:
Frog   132 AVTWWSDKVKEEMGILVRDKGVNSFKMFMAYKDLYMVNDPELYQAFSCCKDIGAIAQVHAENGDL 196

  Fly   212 IAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARH 276
            |::..:::|:.||.|||||||.|||||||||..||..:|:..:||||||||||||:...:|.||.
Frog   197 ISEGAKKMLSLGITGPEGHELCRPEEVEAEATQRAVTIANSVNCPLYVVHVMSKSSAKVIANARR 261

  Fly   277 RYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSD 341
              .|:.:.||.:||.||||.|...|..:...||.|:.||||||.:|||:||.|||||||..||:|
Frog   262 --EGKVVFGEPIAAGLGTDGTNYWHHDWCHAAAFVMGPPLRPDPSTPEYLMNLLANDDLSTTGTD 324

  Fly   342 NCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQ 406
            |||||...|||||.|||||||||||||||||::||||||:|.:|..|||||||:||||||||||:
Frog   325 NCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSSNAAKIFNIYPR 389

  Fly   407 KGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVA 471
            ||:||:|||||||||:|.||||||..|||.|.:|||||||..|||....:..||:..|.|.:...
Frog   390 KGKIAIGSDADIVIWDPQATRTISAQTHHQAVNFNIFEGMVCHGVPLVTIAGGRVVYENGMLHTM 454

  Fly   472 EGFGRFIPTPVRPPFVYDIIEGKVQS-----QPEEQHEEKQNGSM 511
            ||.|::||   |.||. |.:.|::..     ||.....|...|.:
Frog   455 EGHGKYIP---RKPFA-DYVYGRIHQRDAVCQPVPVQREPYKGDV 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	277/452 (61%)
CRMP	NP_730954.2	PRK09060	24..483	CDD:181632	280/458 (61%)
dpys	XP_031760022.1	D-HYD	7..458	CDD:238639	277/452 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20359
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D174151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010