Protein Alignment CRMP and dpysl2

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001121465.1
• Gene: dpysl2 / 100158561
• XenbaseID: XB-GENE-1010783
• Length: 656
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 282/586 - (48%)
• Similarity: 378/586 - (64%)
• Gaps: 35/586 - (5%)

  Fly    14 HLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGID 78
            :|....:|:.||.|:|||.|:||.||:|:|||:||.:|  ..:.:||||:||:|.|.|:||||||
 Frog    93 NLNDKSDRLLIKGGKIVNDDQSFHADIYMEDGLIKQIG--ENLIVPGGVKTIEAHGRMVIPGGID 155

  Fly    79 PHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYG 143
            .||..|.|..|.|:.|||:.|||||:|||||||||.|:|....|::.|:|:||.|||.|.||||.
 Frog   156 VHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYS 220

  Fly   144 LHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAEN 208
            |||.||.|.|.|.||:..|.|:.|||||..:||||..|||.||.:.:||..||.:..:|.|||||
 Frog   221 LHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAEN 285

  Fly   209 GDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELAR 273
            ||:||:...|:|.:||||||||.|||||||||||.:|:..:|:|.:|||||..|||||:...:|:
 Frog   286 GDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQ 350

  Fly   274 ARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLT 338
            ||.  :|..:.||.:.|:||||.:......:...||.|.||||.||.:||:||..||:..|||:.
 Frog   351 ARK--KGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVC 413

  Fly   339 GSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNI 403
            ||.:||||...||:||.:||.||.|.||.|:|||:||::.|.:|.:|..:||||||||||||||:
 Frog   414 GSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNL 478

  Fly   404 YPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNV 468
            ||:|||||||||||:|||:|::.||||..||:...::||||||...|....|:.:|:|..|.|.:
 Frog   479 YPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQGKIVLEEGTL 543

  Fly   469 RVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIP---VQEPISA 530
            ...||.||:||....|.:||..|:.:                  .|.|||. .:|   ...|:..
 Frog   544 HATEGSGRYIPRKPFPDYVYKRIKAR------------------SRLAELR-GVPRGLYDGPVCE 589

  Fly   531 MLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS-----EELDRSGVRACIKVKNPPGGKS 590
            :.....|:....|..::|: :......|:|.:|.||:|     :.:.|   |...::..||||::
 Frog   590 VSVTPKAVTPASSAKTSPA-KQPAQPIRNLHQSGFSLSGAQVDDNIPR---RTTQRIVAPPGGRA 650

  Fly   591 S 591
            :
 Frog   651 N 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	251/452 (56%)
dpysl2	NP_001121465.1	D-HYD	101..550	CDD:238639	251/452 (56%)