Protein Alignment mia and Taf6l

DIOPT Version :10

• Sequence 1: NP_649547.3
• Gene: mia / 40667
• FlyBaseID: FBgn0014342
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_666204.2
• Gene: Taf6l / 225895
• MGIID: 2444957
• Length: 623
• Species: Mus musculus
• Alignment Length: 504
• Identity: 120/504 - (23%)
• Similarity: 200/504 - (39%)
• Gaps: 124/504 - (24%)

  Fly    12 MKTSQNEMPDKDKSFRRHSLSPRSLSAIFFHSTGLHLDDGVAQWLSINVKEDITNLLNEA----G 72
            |::|...|.::::  ||....||....:...||||.|.|.||..|:    ||:...|.||    .
Mouse     1 MQSSTGAMSEREE--RRFVEIPRESVRLMAESTGLELSDEVAALLA----EDVCYRLREATQNSS 59

  Fly    73 KYMRRIRDRRLQLSHIQHAVRMH--DDLC-YDIFFRLVHCDDCKMPPSQKV--LKTVREAVTAEK 132
            ::|:..:.|:|.:.....|:|..  :.:| |.               ||:.  |:..||......
Mouse    60 QFMKHTKRRKLTVEDFNRALRWSSVEAVCGYG---------------SQEALPLRPAREGDLYFP 109

  Fly   133 KDELLVSYPESVQESVPEPVPETSLEPPPMHTGWLKVEQVLLK----PSKRYPLSMEQQNFFELV 193
            :|..:.....::..::|:...||::.   :|..:|..:..|..    ||....|:.:...:::.|
Mouse   110 EDREVSLVELALATNIPKGCAETAVR---VHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQV 171

  Fly   194 TEACVGDLESRRVLALKAISTDPSLEELLPRLTKFIADAVAINVAQQNLPLLLYLMRMVRALLGN 258
            |.|.:||......:||:.:.|:..:..|||   .|:.....:.....:|..|..|:::.|:|:.|
Mouse   172 TRAVLGDDPQLMKVALQDLQTNSKIAALLP---YFVYVVSGVKSVSHDLEQLHRLLQVARSLIRN 233

  Fly   259 QRFSLLQYLHLLLPAVLSCLLAKQVCASPNS-EDHWALREYSGNIMAHIVRQFDAADNGILPRVI 322
            ....|..|:..|:.:||.|:| :.:.||.|. .|||.||:.:..:::||.     ..:|.|  |.
Mouse   234 PHLCLGPYVRSLVGSVLYCVL-EPLAASINPLNDHWTLRDGAALLLSHIF-----WTHGDL--VS 290

  Fly   323 GVYNKALLK---------KPLTTVFGAVIGLGKMGNHAVRACILPQLKYLSEHIDSHMAASNDSP 378
            |:|.:.||.         :||.:.:|||:||..:|..||...:.|   :|..:..:..|..:|
Mouse   291 GLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYP---HLPTYWTNLQAVLDD-- 350

  Fly   379 SSSVDRQAVKYIRHRLMKMCSPVLMGIHQPPDLPEEFMERYGSLGTLMSDGVTVMRTKKQAVAAA 443
             .||....||...|::                        ||::                   ..
Mouse   351 -YSVSNAQVKADGHKV------------------------YGAI-------------------LV 371

  Fly   444 KAEAELKLKNMATEHLNSRGKGSRSVGSNDLVSGTQLPKNGIRPTSQAP 492
            ..|..||:|..|.|. |..|.|.|                |.||....|
Mouse   372 AVERLLKMKAQAAEP-NRGGLGGR----------------GYRPAEDLP 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mia	NP_649547.3	HFD_SF	<47..94	CDD:480273	14/50 (28%)
		TAF6C	181..397	CDD:381749	62/225 (28%)
		HEAT repeat	184..215	CDD:381749	7/30 (23%)
		HEAT repeat	222..257	CDD:381749	8/34 (24%)
		HEAT repeat	267..310	CDD:381749	15/43 (35%)
		HEAT repeat	317..347	CDD:381749	13/38 (34%)
		HEAT repeat	349..396	CDD:381749	11/46 (24%)
Taf6l	NP_666204.2	HFD_TAF6L	19..89	CDD:467056	21/73 (29%)
		TAF6C	160..372	CDD:381749	64/271 (24%)
		HEAT repeat	162..193	CDD:381749	7/30 (23%)
		HEAT repeat	200..232	CDD:381749	8/34 (24%)
		HEAT repeat	242..285	CDD:381749	15/48 (31%)
		HEAT repeat	292..324	CDD:381749	10/31 (32%)
		HEAT repeat	326..371	CDD:381749	13/93 (14%)