DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL44 and Mrpl44

DIOPT Version :9

Sequence 1:	NP_649541.1	Gene:	mRpL44 / 40656	FlyBaseID:	FBgn0037330	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001026820.1	Gene:	Mrpl44 / 301552	RGDID:	1309556	Length:	332	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	110/322 - (34%)
Similarity:	172/322 - (53%)	Gaps:	28/322 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KLLEGSPTVQTRRHIKRWVSPTL-----------RELAHRQKKL-------GPQKPERRSGFVEW 61
            :||:..|     |.:....:|||           |.....||:|       .|..|.|||....|
  Rat     7 RLLQQGP-----RRLLAPAAPTLVPPVRGVKKGFRAAFRFQKELERWRLLRSPPPPVRRSEKPNW 66

  Fly    62 NQRSELFAFGKRLGESFELSELQRAFTEKSFAEREEDRRRQLGIEESD--LQMPHNSDLVEKGQQ 124
            :..:|:.|||.||.|:|.|..|:.||....:.:.||.:|:.||||:..  |.:..|.:|.|:|..
  Rat    67 DYHAEIQAFGSRLQEAFSLDLLKTAFVNSCYIKSEEAKRQNLGIEKEAALLNLKDNQELFEQGLS 131

  Fly   125 IARAYVEAFLQHQLPKVPNEGLQAIASYLLSTETLAHVSTHLGTKDLIQSTEYPPSAESQAKSLH 189
            .:...:..||:.:.|.:|.||::::.::|.....:.||:::|..:.|..|.|:|.......::..
  Rat   132 FSHRCLTQFLEDEFPNLPTEGIESLVNFLTGEAVVCHVASNLAVEQLTLSAEFPVPQPVLRRTFF 196

  Fly   190 AVIGALASSSGIERAFIFVRDFICTQLNQKDLLEVWTPQEPIQLLEKICQERKLGEAEPRLLGDC 254
            ||||||..|||.|||.:|:|||:.||:..|:|.|:||...|:.||.:..::|.:...|.||....
  Rat   197 AVIGALLQSSGPERAALFIRDFLITQMTGKELFEMWTIVNPMGLLVEELKKRNISAPESRLTRQS 261

  Fly   255 GKNTVLAAYQVGIYANRQLLGKGFGEDVKTATETAALDALQSIFDTRDNRRPFDFAIQLEPK 316
            |..|.|..|.||:|.:::|:.:|.||.|..|.|.||..||:.::...:||||:|::   :||
  Rat   262 GSTTALPLYFVGLYCDKRLIAEGPGETVLVAEEEAARVALRKLYGFTENRRPWDYS---KPK 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL44	NP_649541.1	Rnc	72..296	CDD:223644	82/225 (36%)
mRpL44	NP_649541.1	RIBOc	81..219	CDD:197778	47/139 (34%)
Mrpl44	NP_001026820.1	DSRM	236..304	CDD:294045	25/67 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346104
Domainoid	1	1.000	185	1.000	Domainoid score	I3289
eggNOG	1	0.900	-	-		E1_COG0571
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11293
Inparanoid	1	1.050	186	1.000	Inparanoid score	I3834
OMA	1	1.010	-	-		QHG46411
OrthoDB	1	1.010	-	-		D533666at33208
OrthoFinder	1	1.000	-	-		FOG0005847
OrthoInspector	1	1.000	-	-		oto97505
orthoMCL	1	0.900	-	-		OOG6_105063
Panther	1	1.100	-	-	LDO	PTHR11207
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6344
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770