DRSC/TRiP Functional Genomics Resources

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Protein Alignment POLDIP2 and fbxo3

DIOPT Version :10

Sequence 1:NP_730934.1 Gene:POLDIP2 / 40655 FlyBaseID:FBgn0037329 Length:431 Species:Drosophila melanogaster
Sequence 2:NP_001333131.1 Gene:fbxo3 / 553731 ZFINID:ZDB-GENE-050522-269 Length:451 Species:Danio rerio


Alignment Length:257 Identity:59/257 - (22%)
Similarity:100/257 - (38%) Gaps:67/257 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 TNLGTTSQVDPKEVKGKVQTFYQVLIDTRDCPYIRAQTEAVTFLGNQDSNRSLYAIPGLDYVAHE 231
            |.|.....::..|.:.:.:.|||       ||...|          ||.:.....|.|.::.   
Zfish   198 TGLSQYMALETTEGRTRSEIFYQ-------CPDQLA----------QDPSAIDMFITGSNFT--- 242

  Fly   232 DIMPYSSSEKSPLQHELFDKFLTHAPDADPPFVGQDTLKAWQEKNHPWLDMSDVHKE----TTEN 292
                           |.|..::.:....:.|.:.....:.             ||.:    ||.:
Zfish   243 ---------------EWFTSYVDNVVTGEYPIIRDQIFRY-------------VHDKRCVATTGD 279

  Fly   293 VRITVIPFYMGCRETPASSV----YWWRYCIRLE----NLGELSVQLRERHWRIFSLSGTLETVR 349
            :.::|...::    ...|||    :::.|.||:|    .|.|.:.||..|:|:|.:.:|.:|.||
Zfish   280 ITVSVSTSFL----PELSSVHPPHFFFTYRIRIEMAKSALPEKACQLDSRYWKITNANGNVEEVR 340

  Fly   350 GRGVVGQEPILSPRLPAFQYSSHVSLQAPSGHMWG--TFRLEREDGYSFDCKIPPFSLESKP 409
            |.||||:.|:::|. ...:|:|..:....|.:|.|  ||...:.....||..||.|.:...|
Zfish   341 GPGVVGEFPVMTPG-KVHEYASCTTFSTTSEYMEGHYTFHRLKNKEEVFDVSIPRFHMVCPP 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POLDIP2NP_730934.1 YccV-like 72..258 CDD:445467 15/90 (17%)
DUF525 289..407 CDD:470082 40/127 (31%)
fbxo3NP_001333131.1 F-box_FBXO3 9..57 CDD:438856
SMI1_KNR4 117..245 CDD:430545 14/81 (17%)
DUF525 290..380 CDD:461283 32/90 (36%)
Blue background indicates that the domain is not in the aligned region.

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