Protein Alignment PEK and SPA1

DIOPT Version :10

• Sequence 1: NP_649538.1
• Gene: PEK / 40653
• FlyBaseID: FBgn0037327
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_182157.2
• Gene: SPA1 / 819242
• AraportID: AT2G46340
• Length: 1029
• Species: Arabidopsis thaliana
• Alignment Length: 655
• Identity: 129/655 - (19%)
• Similarity: 207/655 - (31%)
• Gaps: 244/655 - (37%)

  Fly   677 NKESSRQR--VLREARTLASC----EHHNIVRYFHSWTETPPTGWQEEEDRKLLAHEL------- 728
            ||..:|..  |::.....:.|    .|.|:     ..|:.||.  :|....||...||
plant    29 NKLDARHNDMVIQSETANSDCPGSSAHRNV-----DLTKPPPP--EEAAGAKLSVEELTLGNYRI 86

  Fly   729 ---STSIQIETP----------------------DDSTMPSLTEQLKEKRQQQL----------- 757
               |.:..:::|                      |..:.|...:|:..:.:|||
plant    87 VQGSNNTNVDSPRAGKFEHLYRLARGSAFRAGDGDLDSQPRDMDQMLSRIRQQLAGAPSERQNLK 151

  Fly   758 --LSWVSDAANSTACSHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAALRA-------E 813
              :|..|| .|..|.|......||:|:.|.........:..:.:...:.||....||       .
plant   152 PFMSRRSD-QNLEAFSERLRAAGENSIMNAPALISEGVQMKTPVSSSNFSQLLLKRAMKGKGVVG 215

  Fly   814 EEDDTDDDYEEDEEQQGDHEKRHRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSGS 878
            :..:|..::..|:: .|..||:...|.|...|.. ..||:                  .||.:|.
plant   216 KNQETPPEFVSDQD-LGSKEKKLDISKSPTPHDV-LPLKS------------------SPKGNGM 260

  Fly   879 DDANDDNKARRKPLTLALAQNHNNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKESLRD 943
            ....|.|.::                       ||..|                       |||:
plant   261 VSHGDGNHSK-----------------------SSIGI-----------------------SLRE 279

  Fly   944 WLRDNRSETRAAHIGDIFHQIVDAVDYVHLKGLIHRDLKPSNIFFSQDGQIK-IGDFG---LVTD 1004
            :||.:.::....|...:|.|:|:.||..|.|.|...||:||........::: ||:||   |.:|
plant   280 FLRSSYAKREKRHGLCLFRQLVELVDSAHSKRLFLLDLRPSLFTLVPSKKLRYIGNFGKNDLESD 344

  Fly  1005 MADIPN----LVAKC-------------------GDQ-----SGLP------------------- 1022
            :.:..|    :|.:.                   |:|     :|.|
plant   345 VDEDLNRRRPVVEESSSGGRDSKKRKMDLHLNSPGNQLQATSTGRPFKRKSPVIDLNMVDARNPD 409

  Fly  1023 SC---------------ARHTQQVGTHL----YMSPEQLLGQHYDYKVDIYSLGLIFFELHVYFS 1068
            ||               ....|.:.|.|    |..||::.|:....|.:||:||::.|||..:..
plant   410 SCELQQQDYIKNLSVSSVSRKQSMSTWLEEQWYTCPEEINGEDIGEKSNIYALGVLLFELLCHCE 474

  Fly  1069 TEMERIKTLRSLRDGQYPKDFAVNYPQQYDLLQQMLSAQPEQRPQTKQ-LKSQL----------- 1121
            :.......:..||....|..|...||::......:|..:|..||..:. |||:|
plant   475 SGEMHAAMMADLRHRILPPTFLSKYPKEAGFCLWLLHPEPSSRPSARDILKSELICEDDSVKSTA 539

  Fly  1122 --RNILQL----------------PHLLSEGQSEQAELAERARRLS------------RSRTFSS 1156
              ..|.:|                ..||.:.|:.:.::.|..||.|            ..|..||
plant   540 AAEEISELLLHFLSSLEVQKKKKASKLLQDIQTLEDDIKEAERRYSSNVSLVRSHGAIEKRVQSS 604

  Fly  1157 SSEPH 1161
            ..:.|
plant   605 PLDEH 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEK	NP_649538.1	Luminal_EIF2AK3	73..401	CDD:188874
		Protein Kinases, catalytic domain	635..1113	CDD:473864	111/563 (20%)
SPA1	NP_182157.2	PLN00181	275..1029	CDD:177776	75/358 (21%)
		WD40 repeat	721..764	CDD:293791
		WD40 repeat	768..805	CDD:293791
		WD40 repeat	812..848	CDD:293791
		WD40 repeat	853..891	CDD:293791
		WD40 repeat	897..940	CDD:293791
		WD40 repeat	1002..1028	CDD:293791