DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and Repin1

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_006236485.1	Gene:	Repin1 / 445541	RGDID:	1549707	Length:	639	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	53/186 - (28%)
Similarity:	75/186 - (40%)	Gaps:	19/186 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 PSAAVIAAAEAAAEAAQQED----------LQEQEMERAAKRRSNFFICDECGTLFHDAFLYTEH 195
            |..::...|||.|......|          |:..:.:...:|.   |.|.|||..|........|
  Rat   432 PLGSLRTPAEAPASLHSCTDCGRSFRLERFLRLHQRQHTGERP---FTCTECGKNFGKKTHLVAH 493

  Fly   196 LNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAH 260
            ...|...|.    |.|.||.:.|::.:.|..||.. |...|.|.|..|.:||........|.:.|
  Rat   494 SRVHSGERP----FACEECGRRFSQGSHLAAHRRD-HAPERPFVCPDCGKAFRHKPYLAAHRRIH 553

  Fly   261 KNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKT 316
            ..|:||.|.:||..||..|.|.:|...|:.: |.:.|..|:..|..:..|:.|.|:
  Rat   554 TGEKPYVCPDCGKAFSQKSNLVSHRRIHTGE-RPYACPDCDRSFSQKSNLITHRKS 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	179..199	CDD:275368	6/19 (32%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	22/69 (32%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..316	CDD:275368	5/18 (28%)
Repin1	XP_006236485.1	C2H2 Zn finger	146..166	CDD:275368
		C2H2 Zn finger	174..194	CDD:275368
		C2H2 Zn finger	205..225	CDD:275368
		COG5048	<225..399	CDD:227381
		C2H2 Zn finger	234..254	CDD:275368
		C2H2 Zn finger	266..286	CDD:275368
		C2H2 Zn finger	325..345	CDD:275368
		zf-H2C2_2	337..362	CDD:290200
		COG5048	<341..612	CDD:227381	53/186 (28%)
		C2H2 Zn finger	353..373	CDD:275368
		zf-H2C2_2	365..390	CDD:290200
		C2H2 Zn finger	381..401	CDD:275368
		C2H2 Zn finger	449..469	CDD:275368	2/19 (11%)
		zf-H2C2_2	462..484	CDD:290200	7/24 (29%)
		C2H2 Zn finger	477..497	CDD:275368	6/19 (32%)
		zf-H2C2_2	489..514	CDD:290200	8/28 (29%)
		C2H2 Zn finger	505..525	CDD:275368	7/20 (35%)
		C2H2 Zn finger	533..553	CDD:275368	5/19 (26%)
		zf-H2C2_2	545..570	CDD:290200	9/24 (38%)
		C2H2 Zn finger	561..581	CDD:275368	8/19 (42%)
		zf-H2C2_2	573..598	CDD:290200	7/25 (28%)
		C2H2 Zn finger	589..609	CDD:275368	6/20 (30%)
		C2H2 Zn finger	617..637	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030