DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14667 and znf1014

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001108370.1	Gene:	znf1014 / 100141333	ZFINID:	ZDB-GENE-080220-9	Length:	508	Species:	Danio rerio

Alignment Length:	322	Identity:	72/322 - (22%)
Similarity:	117/322 - (36%)	Gaps:	93/322 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LKLITGVELTRNQGLPEIVCERCFSELDLATKFRERCIFSQKYLLDIIKKTSDQSTVHVELSSEP 99
            ||...|:.:    ||....|..|      ...||             ||.:.:   ||:.|
Zfish    79 LKQHIGIHI----GLKPFACAEC------GKSFR-------------IKSSLE---VHMRL---- 113

  Fly   100 LDEQLIDADQLETHYDDDQYVC--------YQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEAA 156
                         |..:..:.|        ..||.::||   .|..::.|    ....|......
Zfish   114 -------------HTGEKPFTCSLCGKSFRRSGTFDDHQ---RIHFEEKP----FTCDECGKSFK 158

  Fly   157 QQEDLQEQEMERAAKRRSNFFICDECGTLFHDAFLYTEHLNGHQNRR------------------ 203
            ....||..::..:.::.   |.||:||..:.......:|:..|.|.:
Zfish   159 WANCLQIHKLIHSGEKP---FGCDQCGKRYIQKSELRDHMMSHTNEKPYSCEFCGKGFARLCRFR 220

  Fly   204 -------DMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAHK 261
                   .:|: :.|.:|.|||....|||.|: ::|...|.::|..|.:.|...||..:|.:.|.
Zfish   221 HHQKTHTGVNE-YSCTDCGQTFTTFTLLKAHQ-KIHTEKRPYKCAFCQKTFKQSGAFKKHHRIHS 283

  Fly   262 NERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITRRGL----VAHTKTAPH 319
            .|:|:.|.|||..|...:.||.|...||.: ::|.|:.|...|:.:..|    ::||...|:
Zfish   284 EEKPFACDECGKSFKWENSLQIHKLIHSGE-KQFSCDQCGKKFVQKSDLKTHMMSHTGEKPY 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	9/44 (20%)
		C2H2 Zn finger	179..199	CDD:275368	5/19 (26%)
		C2H2 Zn finger	211..232	CDD:275368	9/20 (45%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-C2H2_8	243..313	CDD:292531	23/73 (32%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..316	CDD:275368	6/22 (27%)
znf1014	NP_001108370.1	C2H2 Zn finger	66..86	CDD:275368	3/6 (50%)
		COG5048	90..476	CDD:227381	67/307 (22%)
		C2H2 Zn finger	94..114	CDD:275368	9/58 (16%)
		C2H2 Zn finger	122..142	CDD:275368	5/22 (23%)
		C2H2 Zn finger	150..170	CDD:275368	3/19 (16%)
		C2H2 Zn finger	178..198	CDD:275368	5/19 (26%)
		C2H2 Zn finger	206..226	CDD:275368	0/19 (0%)
		C2H2 Zn finger	234..254	CDD:275368	9/20 (45%)
		C2H2 Zn finger	262..282	CDD:275368	6/19 (32%)
		C2H2 Zn finger	290..310	CDD:275368	8/19 (42%)
		C2H2 Zn finger	318..338	CDD:275368	4/19 (21%)
		C2H2 Zn finger	346..366	CDD:275368
		C2H2 Zn finger	374..394	CDD:275368
		C2H2 Zn finger	402..422	CDD:275368
		C2H2 Zn finger	430..450	CDD:275368
		C2H2 Zn finger	458..478	CDD:275368
		C2H2 Zn finger	486..503	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100