DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11999 and Sdf2

DIOPT Version :9

Sequence 1:	NP_649527.1	Gene:	CG11999 / 40637	FlyBaseID:	FBgn0037312	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_033169.3	Gene:	Sdf2 / 20316	MGIID:	108019	Length:	219	Species:	Mus musculus

Alignment Length:	216	Identity:	110/216 - (50%)
Similarity:	145/216 - (67%)	Gaps:	13/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ILLLTGL-ALVGSISRGAATESNVVTCGSILKLLNSDYAFRLHSHDVKYGSGSGQQSVTGVEQKE 67
            :|||.|| :.||      |:...||||||::||||:.:..|||||||:|||||||||||||...:
Mouse    14 LLLLGGLWSAVG------ASNMAVVTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVD 72

  Fly    68 DVNSHWVIKAQTGELCERGEPIACGSTVRLEHLSTKKNLHSHHFSSPLSGEQEVSAYGTDGLGDT 132
            |.||:|.|:.:|..:||||.||.||..:||.|::|.:|||||||:|||||.|||||:|.:|.||.
Mouse    73 DSNSYWRIRGKTATVCERGTPIKCGQPIRLTHINTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDY 137

  Fly   133 GDHWEVVCSNENWMRSAHVRLRHIDTGMYLGMSGRSYGRPISGQMEIVGVHKPQHGTRWTTAEGL 197
            .|.|.|:|:...|:|...||.:|..|.:.|.::|..||||||||.|:.|:.:|.....|...||:
Mouse   138 LDDWTVLCNGPYWVRDGEVRFKHSSTDVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGI 202

  Fly   198 FIVPKE--KSSTHDEYAHSEL 216
            |:.|.|  ::..|    |:||
Mouse   203 FMKPSELLRAEVH----HAEL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11999	NP_649527.1	MIR	26..75	CDD:197746	34/48 (71%)
		MIR	86..138	CDD:197746	32/51 (63%)
		MIR	151..>182	CDD:197746	15/30 (50%)
Sdf2	NP_033169.3	MIR	29..80	CDD:197746	34/50 (68%)
		MIR	91..146	CDD:197746	33/54 (61%)
		MIR	148..197	CDD:197746	19/48 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5186
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5045
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3513
Isobase	1	0.950	-	0	Normalized mean entropy	S2064
OMA	1	1.010	-	-		QHG54450
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002719
OrthoInspector	1	1.000	-	-		otm43364
orthoMCL	1	0.900	-	-		OOG6_102590
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	1	1.000	-	-		X2096
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.710