Protein Alignment CtsF and Ctsll3

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_081620.2
• Gene: Ctsll3 / 70202
• MGIID: 1917452
• Length: 331
• Species: Mus musculus
• Alignment Length: 356
• Identity: 127/356 - (35%)
• Similarity: 185/356 - (51%)
• Gaps: 57/356 - (16%)

  Fly   277 VVQA--RHTRSVE--WAEKKT-HKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNL 336
            ||.|  .|..|::  |.|.|| |||                     .|....|.|.| .::..|.
Mouse    14 VVSAAPAHNPSLDAVWEEWKTKHKK---------------------TYNMNDEGQKR-AVWENNK 56

  Fly   337 KTIEELNANEMGSAKYG----ITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYH----GE 393
            |.| :|:..:....|:|    :..|.|:|::|::|....:|..:.|      .::..:.    |:
Mouse    57 KMI-DLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTK------MMMKVFQEPLLGD 114

  Fly   394 LPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSAC 456
            :||..|||....||.||:|||||||||||..|::||....|||:|...|.|.|:||..:  :..|
Mouse   115 VPKSVDWRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGC 179

  Fly   457 NGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLAN 521
            :|||.|.|::.:||.|||:....|||:|....|.:|...|...|.|||:: :.:|.|:.:.:...
Mouse   180 DGGLPDLAFQYVKDNGGLDTSVSYPYEALNGTCRYNPKNSAATVTGFVNV-QSSEDALMKAVATV 243

  Fly   522 GPISIGINA--NAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYG-VSDYPNFHKTLPYWIVKNSW 583
            ||||:||:.  .:.|||:.|:.  ::..||...|||.||||||| .||      ...||:|||||
Mouse   244 GPISVGIDTKHKSFQFYKEGMY--YEPDCSSTVLDHAVLVVGYGEESD------GRKYWLVKNSW 300

  Fly   584 GPRWGEQGYYRVYRG-DNTCGVSEMATSAVL 613
            |..||..||.::.:. :|.||::..|:..|:
Mouse   301 GRDWGMNGYIKMAKDRNNNCGIASDASYPVV 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	13/60 (22%)
		Peptidase_C1A	395..611	CDD:239068	96/221 (43%)
Ctsll3	NP_081620.2	Inhibitor_I29	29..87	CDD:214853	20/80 (25%)
		Peptidase_C1	115..330	CDD:425470	96/223 (43%)