Protein Alignment CtsF and Ctsr

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_064680.1
• Gene: Ctsr / 56835
• MGIID: 1861723
• Length: 334
• Species: Mus musculus
• Alignment Length: 323
• Identity: 115/323 - (35%)
• Similarity: 172/323 - (53%)
• Gaps: 36/323 - (11%)

  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGIT----EFADMTSSE 364
            :|..:..:::::.:.| |..|.:::..::.:.||.| :|:..|....|.|.|    ||.|.|..|
Mouse    25 LDAEWQDWKIKYNKSY-SLKEEKLKRVVWEEKLKMI-KLHNRENSLGKNGFTMKMNEFGDQTDEE 87

  Fly   365 YKE---RTGLWQRDEAKA----TGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFS 422
            :::   ...:|...|.|:    ..||.         |||..|||:|..||.|:.||.|.:||||:
Mouse    88 FRKMMIEISVWTHREGKSIMKREAGSI---------LPKFVDWRKKGYVTPVRRQGDCDACWAFA 143

  Fly   423 VTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAK 485
            |||.||.....:||:|...|.|.|:||...  ::.|.||...||::.:...||||.||.|||:.|
Mouse   144 VTGAIEAQAIWQTGKLTPLSVQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLESEATYPYEGK 208

  Fly   486 KNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQF--YRGGVSHPWKALC 548
            ...|.:|...|..::.|||.||:..:..|.. :...|||:.||:|:...|  |:||:.|  :..|
Mouse   209 DGPCRYNPKNSKAEITGFVSLPQSEDILMAA-VATIGPITAGIDASHESFKNYKGGIYH--EPNC 270

  Fly   549 SKKNLDHGVLVVGYGVS--DYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DNTCGVSEMA 608
            |...:.|||||||||..  :....|    ||::|||||.|||.:||.::.:. :|.||::..|
Mouse   271 SSDTVTHGVLVVGYGFKGIETDGNH----YWLIKNSWGKRWGIRGYMKLAKDKNNHCGIASYA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	15/60 (25%)
		Peptidase_C1A	395..611	CDD:239068	92/221 (42%)
Ctsr	NP_064680.1	Inhibitor_I29	29..87	CDD:214853	15/59 (25%)
		Peptidase_C1A	116..332	CDD:239068	92/221 (42%)