Protein Alignment CtsF and cts12

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_695425.1
• Gene: cts12 / 567046
• ZFINID: ZDB-GENE-050208-336
• Length: 349
• Species: Danio rerio
• Alignment Length: 376
• Identity: 121/376 - (32%)
• Similarity: 178/376 - (47%)
• Gaps: 66/376 - (17%)

  Fly   255 IWTKVWVRKDEHEITFKCRNQPVVQARHTRSVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRY 319
            :|..|.|..:..|               ....||...|  |||...:|:
Zfish    23 VWAPVQVASESEE---------------EAPTEWNLWK--KKHEISYDE---------------- 54

  Fly   320 VSTAERQMRLRIFRQNLKTIEELNANE----MGSAKYGITEFADMTSSEYKERTGLWQRDEAKAT 380
              .:|...|..|:..|::.|.: |.|:    :...|..:.::.|:||.|||...|    .:.|.|
Zfish    55 --ESEDVHRKTIWETNMQKIWK-NNNDFSFGLSMFKMAMNKYGDLTSVEYKRLLG----SKIKGT 112

  Fly   381 GG------SAAVVPAYHGEL-PKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGEL 438
            |.      ||.::......| ....|:|.|..||:||:||.|||||:||.||.|||.....||.|
Zfish   113 GNRKGKITSAQMLRLNAKRLGVTNIDYRAKGYVTEVKDQGYCGSCWSFSTTGAIEGQMYKHTGRL 177

  Fly   439 KEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQ-CHFNRTLSHVQV 500
            ...|||:|:||..:  ...|:|..|.|||..:.: ..||....|||.:...| |.:.:.|:...:
Zfish   178 VSLSEQQLVDCSRSYGTYGCSGAWMANAYDYVIN-NALESSDTYPYTSVDTQPCFYEKNLAMAGI 241

  Fly   501 AGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGVSHPWKALCSKKNLDHGVLVVGYG 563
            :.:..:|.|||.|:.:.:...||:|:.|:|:  :..||..|:..  ::.|:..||:|.|||||||
Zfish   242 SDYRFVPAGNEQALADAVATVGPVSVAIDADNPSFLFYSSGIYK--ESNCNPNNLNHAVLVVGYG 304

  Fly   564 VSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYR-GDNTCGVSEMATSAVL 613
            ..:..:      |||:|||||..|||.||.|:.| |.||||::..|...::
Zfish   305 SEEGTD------YWIIKNSWGTGWGEGGYMRMIRNGKNTCGIASYALYPII 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	11/60 (18%)
		Peptidase_C1A	395..611	CDD:239068	89/221 (40%)
cts12	XP_695425.1	Inhibitor_I29	41..101	CDD:462410	17/80 (21%)
		Peptidase_C1A	135..347	CDD:239068	89/220 (40%)