DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and AgaP_AGAP011828

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_001689282.1	Gene:	AgaP_AGAP011828 / 5667926	VectorBaseID:	AGAP011828	Length:	344	Species:	Anopheles gambiae

Alignment Length:	327	Identity:	125/327 - (38%)
Similarity:	190/327 - (58%)	Gaps:	25/327 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 FDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNAN-EMGSAKY--GITEFADMTS 362
            |:.|...:..|:::..::|.|..|.::|::|:.||...|.:.|.. ::|..|:  .:.::||:..
Mosquito    21 FELVKEEWTAFKLQHRKKYDSETEERIRMKIYVQNKHKIAKHNQRYDLGQEKFRLRVNKYADLLH 85

  Fly   363 SEY--------KERTGLWQ--RDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGS 417
            .|:        :..:|..|  |.|.|........:...:.::|...|||.|.||||||:||.|||
Mosquito    86 EEFVHTLNGFNRSVSGKGQLLRGELKPIEEPVTWIEPANVDVPTAMDWRTKGAVTQVKDQGHCGS 150

  Fly   418 CWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEY 480
            ||:||.||.:||.:..|||:|...|||.|:||...  ::.||||:||.|::.|||..|::.|..|
Mosquito   151 CWSFSATGALEGQHFRKTGKLVSLSEQNLVDCSQKYGNNGCNGGMMDFAFQYIKDNKGIDTEKSY 215

  Fly   481 PYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGVSHP 543
            ||:|..::||:|.........||||:|:|||.|:.:.|...||:|:.|:|:  :.|||..||.
Mosquito   216 PYEAIDDECHYNPKAVGATDKGFVDIPQGNEKALMKALATVGPVSVAIDASHESFQFYSEGVY-- 278

  Fly   544 WKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DNTCGVSEM 607
            ::..|..:.||||||.||||.::...     .||:||||||..||:|||.::.|. ||.||::..
Mosquito   279 YEPQCDSEQLDHGVLAVGYGTTEDGE-----DYWLVKNSWGTTWGDQGYVKMARNRDNHCGIATT 338

  Fly   608 AT 609
            |:
Mosquito   339 AS 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	14/59 (24%)
		Peptidase_C1A	395..611	CDD:239068	103/220 (47%)
AgaP_AGAP011828	XP_001689282.1	PTZ00203	6..343	CDD:185513	125/327 (38%)
		Inhibitor_I29	28..87	CDD:214853	14/58 (24%)
		Peptidase_C1	127..343	CDD:278538	103/221 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D71650at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820