Protein Alignment CtsF and Ctsrl1

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001017509.1
• Gene: Ctsrl1 / 498688
• RGDID: 1562210
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 343
• Identity: 119/343 - (34%)
• Similarity: 173/343 - (50%)
• Gaps: 62/343 - (18%)

  Fly   287 EWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAK 351
            ||.|.|  ||:...:                   |..|.::|..::.:|||.| :|:..|.|..|
  Rat    28 EWQEWK--KKYDKSY-------------------SLEEEELRRAVWEENLKMI-KLHNGENGLGK 70

  Fly   352 YGIT----EFADMTSSEYKE----------RTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQ 402
            .|.|    ||.|.|..|:::          |.|   :...|...||.         .||..|||:
  Rat    71 NGFTMEINEFGDTTGEEFRKMMVEFPVQTHREG---KSIMKRAAGSI---------FPKFVDWRK 123

  Fly   403 KDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAY 465
            |..||.|:.||:|.:||||||||.||.....::|:|...|.|.|:||...  ::.|.||...||:
  Rat   124 KGYVTPVRRQGNCNACWAFSVTGAIEAQTIWQSGKLIPLSVQNLVDCSKPQGNNGCLGGDTYNAF 188

  Fly   466 KAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA 530
            :.:...|||:.||.|||:.|...|.:|...|..::.|||.||:..:..|.. :...||||.||:|
  Rat   189 QYVLHNGGLQSEATYPYEGKDGPCRYNPKNSSAEITGFVSLPESEDILMVA-VATIGPISAGIDA 252

  Fly   531 N--AMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGV--SDYPNFHKTLPYWIVKNSWGPRWGEQG 591
            :  :.:||:.|:.|  :..||..::.|||||||||.  :|....|    ||::|||||.:||.:|
  Rat   253 SHESFKFYKKGIYH--EPNCSSNSVTHGVLVVGYGFKGNDTGGDH----YWLIKNSWGKQWGIRG 311

  Fly   592 YYRVYRG-DNTCGVSEMA 608
            |.::.:. :|.|.::..|
  Rat   312 YMKITKDKNNHCAIASYA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	17/60 (28%)
		Peptidase_C1A	395..611	CDD:239068	90/221 (41%)
Ctsrl1	NP_001017509.1	Inhibitor_I29	29..87	CDD:214853	22/79 (28%)
		Peptidase_C1A	116..332	CDD:239068	90/221 (41%)