Protein Alignment CtsF and CtsK1

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_620470.1
• Gene: CtsK1 / 39547
• FlyBaseID: FBgn0250848
• Length: 549
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 140/456 - (30%)
• Similarity: 205/456 - (44%)
• Gaps: 55/456 - (12%)

  Fly   186 ILGRHKPYDEEAAKAQLQKSLDKL----TAGE-------------GPHYKI----VKVYSASRQV 229
            ||...||:.....::.|..:.||.    |.|:             .|||..    :.|....|..
  Fly   113 ILPDAKPFSLVGTESFLGYTCDKFRLESTIGQKKNIYTLWVRYKKSPHYPSSRMPIPVRYEMRGY 177

  Fly   230 DSGILTRIDADLIDGSEEQHRCIVDIWTKVWVRKDEHEITFKCRNQPVVQARHTRSVEWAEKKTH 294
            ::.:.:..|...:|....:|.   ||..:|:    |.:.:.:|...|.....|..:....::...
  Fly   178 NTLLGSHYDHYYLDYDSYEHD---DIPNEVF----EIDDSLQCVGFPGPGTGHYATFNPMQEFIS 235

  Fly   295 KKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFAD 359
            ....|    ||..|:.|:.:.|..|.|..|.:.|..||||||:.|...|..:: :....:...||
  Fly   236 GTDEH----VDKAFHHFKRKHGVAYHSDTEHEHRKNIFRQNLRYIHSKNRAKL-TYTLAVNHLAD 295

  Fly   360 MTSSEYKERTGLWQRDEAKATGGSAAV-VPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSV 423
            .|..|.|.|.| ::......||..... ||.|..|:|.::|||...|||.||:|..|||||:|..
  Fly   296 KTEEELKARRG-YKSSGIYNTGKPFPYDVPKYKDEIPDQYDWRLYGAVTPVKDQSVCGSCWSFGT 359

  Fly   424 TGNIEGLYAVKT-GELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEY-PYKA 484
            .|::||.:.:|. |.|...|:|.|:||...  ::.|:||.....|:.:...||:..|.|| ||..
  Fly   360 IGHLEGAFFLKNGGNLVRLSQQALIDCSWAYGNNGCDGGEDFRVYQWMLQSGGVPTEEEYGPYLG 424

  Fly   485 KKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINAN--AMQFYRGGVSHPWKAL 547
            :...||.|.......:.|||::...:..|.:..||.:||:|:.|:|:  ...||..||.  ::..
  Fly   425 QDGYCHVNNVTLVAPIKGFVNVTSNDPNAFKLALLKHGPLSVAIDASPKTFSFYSHGVY--YEPT 487

  Fly   548 CSKKN----LDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMA 608
            |  ||    |||.||.||||..:..:      ||:|||||...||..||..:....|.|||..|.
  Fly   488 C--KNDVDGLDHAVLAVGYGSINGED------YWLVKNSWSTYWGNDGYILMSAKKNNCGVMTMP 544

  Fly   609 T 609
            |
  Fly   545 T 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	18/56 (32%)
		Peptidase_C1A	395..611	CDD:239068	85/225 (38%)
CtsK1	NP_620470.1	Inhibitor_I29	245..300	CDD:214853	18/55 (33%)
		Peptidase_C1A	331..547	CDD:239068	85/225 (38%)