Protein Alignment CtsF and Tinag

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_036163.3
• Gene: Tinag / 26944
• MGIID: 1349477
• Length: 475
• Species: Mus musculus
• Alignment Length: 340
• Identity: 81/340 - (23%)
• Similarity: 123/340 - (36%)
• Gaps: 101/340 - (29%)

  Fly   339 IEELNANEMGSAKYGITEFADMTSSE-YKERTG-------LWQRDEAKATGGSAAVVP-----AY 390
            |:.:|..:.|......::|..||..| :|.|.|       |...:|..|:....|.:|     :|
Mouse   160 IDHINKGDYGWTAQNYSQFWGMTLEEGFKFRLGTLPPSPMLLSMNEMTASFPPRADLPEIFIASY 224

  Fly   391 ------HGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVK-----TGELKEFSEQ 444
                  ||.|                :|.:|.:.||||.........|::     |..|   |.|
Mouse   225 KWPGWTHGPL----------------DQKNCAASWAFSTASVAADRIAIQSKGRYTANL---SPQ 270

  Fly   445 ELLDCDTTD-SACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCH------------------ 490
            .|:.|...: ..||.|.:|.|:..::. .||...|.||....:|..:
Mouse   271 NLISCCAKNRHGCNSGSIDRAWWFLRK-RGLVSHACYPLFKDQNTTNNICAMASRSDGRGKRHAT 334

  Fly   491 ------FNRTLSHVQVAGFVDLP----KGNETAMQEWLLANGPISIGINANAMQ------FYRGG 539
                  |.::....|.:     |    ..|||.:...::.|||:..     .||      :|:.|
Mouse   335 KPCPNSFEKSNRIYQCS-----PPYRVSSNETEIMREIIQNGPVQA-----IMQVHEDFFYYKTG 389

  Fly   540 V--------SHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVY 596
            :        ..|.|   .||...|.|.:.|:|........|. .:||..||||..|||.||:|:.
Mouse   390 IYRHVVSTNEEPEK---YKKLRTHAVKLTGWGTLRGARGKKE-KFWIAANSWGKSWGENGYFRIL 450

  Fly   597 RGDNTCGVSEMATSA 611
            ||.|...:.::..:|
Mouse   451 RGVNESDIEKLIIAA 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	7/26 (27%)
		Peptidase_C1A	395..611	CDD:239068	61/263 (23%)
Tinag	NP_036163.3	Somatomedin_B	60..105	CDD:470596
		VWC	119..>166	CDD:450195	2/5 (40%)
		Peptidase_C1A_CathepsinB	217..465	CDD:239111	66/281 (23%)