DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12163 and R09F10.1

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_509408.1	Gene:	R09F10.1 / 181087	WormBaseID:	WBGene00019986	Length:	383	Species:	Caenorhabditis elegans

Alignment Length:	331	Identity:	112/331 - (33%)
Similarity:	171/331 - (51%)	Gaps:	33/331 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 SHRFDKVDH--LFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADM 360
            :|:.:.:.|  :|..|.::|.|:|.|..|.:.|.:||.:|:...|......:| ....:.||.|.
Worm    70 NHKMENLKHEQMFNDFILKFDRKYTSVEEFEYRYQIFLRNVIEFEAEEERNLG-LDLDVNEFTDW 133

  Fly   361 TSSEYKERTGLWQRDEAKATGGSAAVVPAYHGEL-------PKEFDWRQKDAVTQVKNQGSCGSC 418
            |..|.::..     .|.|.|..... .|.:.|..       |...|||::..:|.:||||.||||
Worm   134 TDEELQKMV-----QENKYTKYDFD-TPKFEGSYLETGVIRPASIDWREQGKLTPIKNQGQCGSC 192

  Fly   419 WAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYK 483
            |||:...::|...|:|.|:|...||||::|||..::.|:||....|.|.:|: .|||.|.||||.
Worm   193 WAFATVASVEAQNAIKKGKLVSLSEQEMVDCDGRNNGCSGGYRPYAMKFVKE-NGLESEKEYPYS 256

  Fly   484 A-KKNQCHFNRTLSHVQVAGFVD---LPKGNETAMQEWLLANGPISIGIN-ANAMQFYRGGVSHP 543
            | |.:||......:.|    |:|   :...||..:..|:...||::.|:| ..||..||.|:.:|
Worm   257 ALKHDQCFLKENDTRV----FIDDFRMLSNNEEDIANWVGTKGPVTFGMNVVKAMYSYRSGIFNP 317

  Fly   544 WKALCSKKNLD-HGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEM 607
            ....|::|::. |.:.::|||...      ...|||||||||..||..||:|:.||.|:||::..
Worm   318 SVEDCTEKSMGAHALTIIGYGGEG------ESAYWIVKNSWGTSWGASGYFRLARGVNSCGLANT 376

  Fly   608 ATSAVL 613
            ..:.::
Worm   377 VVAPII 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	17/56 (30%)
		Peptidase_C1A	395..611	CDD:239068	87/221 (39%)
R09F10.1	NP_509408.1	Inhibitor_I29	82..138	CDD:285458	17/56 (30%)
R09F10.1	NP_509408.1	Peptidase_C1	169..381	CDD:278538	87/222 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820