Protein Alignment CtsF and cpr-6

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_741818.1
• Gene: cpr-6 / 180931
• WormBaseID: WBGene00000786
• Length: 379
• Species: Caenorhabditis elegans
• Alignment Length: 258
• Identity: 71/258 - (27%)
• Similarity: 112/258 - (43%)
• Gaps: 59/258 - (22%)

  Fly   393 ELPKEFD----WRQKDAVTQVKNQGSCGSCWAF-SVTGNIEGLYAVKTGELK-EFSEQELLD-CD 450
            ::|:.||    |.:.|::..:::|.|||||||| :|....:.:.....|||: ..|..:||. |.
 Worm   104 DIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCCK 168

  Fly   451 TTDSACNGGLMDNAYKA-IKD--IGGLEYEAE-----YPYKAKKNQCHFNRTLSHVQ-------- 499
            :....||||....|::. :||  :.|..|.|.     ||:.    .|..:...:|..
 Worm   169 SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFP----PCEHHSKKTHFDPCPHDLYP 229

  Fly   500 --------VAGFVDLP--------------KGNETAMQEWLLANGPISIGINA-NAMQFYRGGVS 541
                    |:.:.|..              |.:..|:|:.|:.:||:.|.... .....|.|||
 Worm   230 TPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGV- 293

  Fly   542 HPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGV 604
              :.....|....|.|.::|:|:.|      .:|||.|.|||...|||.|::|:.||.:.||:
 Worm   294 --YVHTGGKLGGGHAVKLIGWGIDD------GIPYWTVANSWNTDWGEDGFFRILRGVDECGI 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410
		Peptidase_C1A	395..611	CDD:239068	71/256 (28%)
cpr-6	NP_741818.1	Peptidase_C1A_CathepsinB	106..355	CDD:239111	71/256 (28%)