Protein Alignment CtsF and cpr-3

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_506790.1
• Gene: cpr-3 / 180033
• WormBaseID: WBGene00000783
• Length: 370
• Species: Caenorhabditis elegans
• Alignment Length: 340
• Identity: 76/340 - (22%)
• Similarity: 136/340 - (40%)
• Gaps: 92/340 - (27%)

  Fly   330 RIFRQNLKTIE--------ELNANEMGSAKYGI--TEFADMTSSEYKERTGLWQRDEAKATGGSA 384
            ::...::.|::        |::..||   |:.:  .:||:....:....:.|:.|.|
 Worm    33 KVLVDHVNTVQTSWVAEHNEISEFEM---KFKVMDVKFAEPLEKDSDVASELFVRGE-------- 86

  Fly   385 AVVPAYHGELPKEFDWRQK----DAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKE--FSE 443
             :||.   .||..||.|:|    :.:..::||.:|||||||.....|.....:::...::  .|.
 Worm    87 -IVPE---PLPDTFDAREKWPDCNTIKLIRNQATCGSCWAFGAAEVISDRVCIQSNGTQQPVISV 147

  Fly   444 QELLDC--DTTDSACNGGLMDNAYK------AIK--DIGG---LEY------------------- 476
            :::|.|  .|....|.||....|.:      |:.  |.||   :.|
 Worm   148 EDILSCCGTTCGYGCKGGYSIEALRFWASSGAVTGGDYGGHGCMPYSFAPCTKNCPESTTPSCKT 212

  Fly   477 --EAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA-NAMQFYRG 538
              ::.|..:..|...|:..:...|.....|       |.:|..:...||:...... .....|:.
 Worm   213 TCQSSYKTEEYKKDKHYGASAYKVTTTKSV-------TEIQTEIYHYGPVEASYKVYEDFYHYKS 270

  Fly   539 GVSHPWKALCSKKNL-DHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTC 602
            ||.|    ..|.|.: .|.|.::|:||.:      .:.||::.||||..:||:|::::.||.|.|
 Worm   271 GVYH----YTSGKLVGGHAVKIIGWGVEN------GVDYWLIANSWGTSFGEKGFFKIRRGTNEC 325

  Fly   603 --------GVSEMAT 609
                    |::::.|
 Worm   326 QIEGNVVAGIAKLGT 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	7/44 (16%)
		Peptidase_C1A	395..611	CDD:239068	63/265 (24%)
cpr-3	NP_506790.1	Peptidase_C1A_CathepsinB	93..334	CDD:239111	61/257 (24%)