Protein Alignment CtsF and cpz-2

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_506318.1
• Gene: cpz-2 / 179818
• WormBaseID: WBGene00000789
• Length: 467
• Species: Caenorhabditis elegans
• Alignment Length: 465
• Identity: 113/465 - (24%)
• Similarity: 180/465 - (38%)
• Gaps: 141/465 - (30%)

  Fly   206 LDKLTAGE---GPHYKIVKVYSASRQVDSGILTRIDADLIDGSEEQ---HRCIVD---IWTKVWV 261
            :|||.|.|   |..|. :|:     :|::.:...:| |:.|.|||.   .|.:.|   ::.|.:.
 Worm    36 MDKLPAPEELGGEEYD-MKI-----EVNNVVEEMVD-DMEDSSEEDTPLARVVNDDDLLYKKGFH 93

  Fly   262 RKDEHEITFKCRNQPVVQARHTRSVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQ 326
            .....|:..|. |:|||                                       ||.:.|:..
 Worm    94 LDSPFELNKKV-NKPVV---------------------------------------RYPNIAKNN 118

  Fly   327 MRLR-------IFRQNLKTI------EELNANEMGSAKY--GITE-----FADMTSSEYKERTGL 371
            .::|       .|.:::..|      .:::.:.|..||.  |..|     ..|| |||.:|.:..
 Worm   119 QKIREEIVYPADFDEHVVEILDSRKERKIDLSPMIKAKLEKGYYEPNDEALVDM-SSESEESSEE 182

  Fly   372 WQRD----------------EAKATGGSAAVVPAYHGELPKEFDWRQKDAV---TQVKNQG---S 414
            |:..                |:|..............:||..:|||....|   :..:||.   .
 Worm   183 WEEARPYLKCGCLKKSGKVFESKTAPREWESSSFKSNDLPTGWDWRNVSGVNYCSPTRNQHIPVY 247

  Fly   415 CGSCWAFSVTGNIEGLYAV-KTGE--LKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEY 476
            |||||.|..||.:...:.| :.|.  :.:.|.||::||:...: |.||.:.|..:..| |.||..
 Worm   248 CGSCWVFGTTGALNDRFNVARKGRWPMTQLSPQEIIDCNGKGN-CQGGEIGNVLEHAK-IQGLVE 310

  Fly   477 EAEYPYKAKKNQCH----------------FNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPIS 525
            |....|:|...:|:                .|.|..:|:..|.|   :|.:..|.| :...|||:
 Worm   311 EGCNVYRATNGECNPYHRCGSCWPNECFSLTNYTRYYVKDYGQV---QGRDKIMSE-IKKGGPIA 371

  Fly   526 IGINAN---AMQFYRGGVSHPWKALCSKKNLD--HGVLVVGYGVSDYPNFHKTLPYWIVKNSWGP 585
            ..|.|.   ..::.:|..|       .|.:|:  |.:.:.|:||.:     ..:.|||.:||||.
 Worm   372 CAIGATKKFEYEYVKGVYS-------EKSDLESNHIISLTGWGVDE-----NGVEYWIARNSWGE 424

  Fly   586 RWGEQGYYRV 595
            .|||.|::||
 Worm   425 AWGELGWFRV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	15/76 (20%)
		Peptidase_C1A	395..611	CDD:239068	68/231 (29%)
cpz-2	NP_506318.1	Peptidase_C1A_CathepsinX	221..461	CDD:239149	69/232 (30%)