Protein Alignment CtsF and tag-196

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_505215.2
• Gene: tag-196 / 179240
• WormBaseID: WBGene00007055
• Length: 477
• Species: Caenorhabditis elegans
• Alignment Length: 489
• Identity: 192/489 - (39%)
• Similarity: 260/489 - (53%)
• Gaps: 80/489 - (16%)

  Fly   166 EKARLLNEKY----VHRSRRSANDILGRHKPYDEEAAKAQLQKS--LDKLTAGEGPHYKI----V 220
            |:.:||.||:    |.:..:.:||           |.|.:|.::  :::..:| |.||.|    |
 Worm    27 EEDQLLYEKFARHGVEKFNQQSND-----------AYKWELDRTWEVERKLSG-GIHYSIFVTLV 79

  Fly   221 KVYSASRQVDSGILTRIDADLIDGSEEQHRCIVDIWTK-----------VWVRKDEHEITFKCRN 274
            |......|.|      ::......::...:|.|:|..:           |.:|..|.|.|   ||
 Worm    80 KTDCKKGQTD------VEGKKCRKTDTLKKCQVEISRRVKRHGYGLKDIVHIRNCEEEFT---RN 135

  Fly   275 -----QPVVQARHTRSVEWAEKKTHKKHSHRFDKVDHLFYKFQVRFGRRYVSTAERQMRLRIFRQ 334
                 ...:|..|..|:...|.:..|....|...:.:.|..|..|..::|.:..|...|.|:|::
 Worm   136 IDKFDHRKIQLTHDDSITVQELRKAKIIRPRDYVIWNSFLDFVDRHEKKYTNKREVLKRFRVFKK 200

  Fly   335 NLKTIEELNANEMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAY--------- 390
            |.|.|.||..||.|:|.||.|:|:|||:.|:|:....:|.::           |.|
 Worm   201 NAKVIRELQKNEQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQ-----------PVYPMEQANFEK 254

  Fly   391 ------HGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDC 449
                  ..:||:.||||:|.|||||||||:||||||||.|||:||.:.:...:|...|||||:||
 Worm   255 HDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDC 319

  Fly   450 DTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAM 514
            |:.|..|||||..||||.|..:||||.|..|||..:...||..|....|.:.|.|:||. :|..|
 Worm   320 DSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEM 383

  Fly   515 QEWLLANGPISIGINANAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIV 579
            |:||:..||||||:|||.:||||.||.||:|..|....|:||||:||||...      ..|||||
 Worm   384 QKWLVTKGPISIGLNANTLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDG------RKPYWIV 442

  Fly   580 KNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
            ||||||.|||.||:::|||.|.|||.||||||::
 Worm   443 KNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALV 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	24/56 (43%)
		Peptidase_C1A	395..611	CDD:239068	124/215 (58%)
tag-196	NP_505215.2	CY	23..>91	CDD:447698	20/81 (25%)
		Inhibitor_I29	174..231	CDD:462410	24/56 (43%)
		Peptidase_C1	264..475	CDD:425470	126/217 (58%)