Protein Alignment CtsF and Ctsh

DIOPT Version :10

• Sequence 1: NP_730901.1
• Gene: CtsF / 40628
• FlyBaseID: FBgn0260462
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_031827.2
• Gene: Ctsh / 13036
• MGIID: 107285
• Length: 333
• Species: Mus musculus
• Alignment Length: 313
• Identity: 102/313 - (32%)
• Similarity: 157/313 - (50%)
• Gaps: 20/313 - (6%)

  Fly   304 VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEYKER 368
            ::...:|..::..::..|:.|...||::|..|.:.|:..|... .:.|..:.:|:||:.:|.|.:
Mouse    28 IEKFHFKSWMKQHQKTYSSVEYNHRLQMFANNWRKIQAHNQRN-HTFKMALNQFSDMSFAEIKHK 91

  Fly   369 TGLWQRDEAKATGGSAAVVPAY---HGELPKEFDWRQK-DAVTQVKNQGSCGSCWAFSVTGNIEG 429
            . ||...:     ..:|....|   .|..|...|||:| :.|:.|||||:|||||.||.||.:|.
Mouse    92 F-LWSEPQ-----NCSATKSNYLRGTGPYPSSMDWRKKGNVVSPVKNQGACGSCWTFSTTGALES 150

  Fly   430 LYAVKTGELKEFSEQELLDCDT--TDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFN 492
            ..|:.:|::...:||:|:||..  .:..|.|||...|::.|....|:..|..|||..|.:.|.||
Mouse   151 AVAIASGKMLSLAEQQLVDCAQAFNNHGCKGGLPSQAFEYILYNKGIMEEDSYPYIGKDSSCRFN 215

  Fly   493 RTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANA-MQFYRGGVSHPWKALCSKKNLDHG 556
            ...:...|...|::...:|.||.|.:....|:|....... ...|:.||........:...::|.
Mouse   216 PQKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVTEDFLMYKSGVYSSKSCHKTPDKVNHA 280

  Fly   557 VLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMAT 609
            ||.||||..:      .|.|||||||||.:|||.||:.:.||.|.||::..|:
Mouse   281 VLAVGYGEQN------GLLYWIVKNSWGSQWGENGYFLIERGKNMCGLAACAS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	13/56 (23%)
		Peptidase_C1A	395..611	CDD:239068	82/219 (37%)
Ctsh	NP_031827.2	Inhibitor_I29	33..88	CDD:462410	13/55 (24%)
		Peptidase_C1A	115..329	CDD:239068	82/219 (37%)