DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12163 and AgaP_AGAP001960

DIOPT Version :9

Sequence 1:	NP_730901.1	Gene:	CG12163 / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	XP_321102.4	Gene:	AgaP_AGAP001960 / 1281163	VectorBaseID:	AGAP001960	Length:	302	Species:	Anopheles gambiae

Alignment Length:	182	Identity:	62/182 - (34%)
Similarity:	92/182 - (50%)	Gaps:	6/182 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   307 LFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELN-ANEMGSAKYGI--TEFADMTSSEYKER 368
            ||..:.....::|.:......|.....:|::.|:|.| |.|.||.::.:  ..||||.:|||::|
Mosquito   114 LFRSYMQTHRKKYYAKYRADRRRSALMENMQEIQEHNKAYEAGSNRFRMAPNAFADMHNSEYRKR 178

  Fly   369 TGLWQRD-EAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYA 432
            ....:.| ..|.....|..:.:...|||.|.|||:|...|...||.|||||:||||...|.....
Mosquito   179 LVRLKTDPHRKVEPAVADEIVSSSNELPAELDWREKGFKTAPANQKSCGSCYAFSVAYAISAQLM 243

  Fly   433 VKTGELKEFSEQELLDCDTTDS--ACNGGLMDNAYKAIKDIGGLEYEAEYPY 482
            ...|.::..|||:::||.|.:.  .|.||.:.|..|.::..||:..|.:|||
Mosquito   244 KHIGRVELVSEQQMVDCSTANGNLGCGGGSLRNTLKYLEQAGGVMREVDYPY 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12163	NP_730901.1	CY	194..272	CDD:298856
		Inhibitor_I29	308..365	CDD:285458	16/59 (27%)
		Peptidase_C1A	395..611	CDD:239068	37/90 (41%)
AgaP_AGAP001960	XP_321102.4	Inhibitor_I29	115..175	CDD:285458	16/59 (27%)
AgaP_AGAP001960	XP_321102.4	Pept_C1	205..>301	CDD:214761	38/91 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810