DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc6 and UBE2R2

DIOPT Version :9

Sequence 1:	NP_001246916.1	Gene:	Ubc6 / 40610	FlyBaseID:	FBgn0004436	Length:	151	Species:	Drosophila melanogaster
Sequence 2:	NP_060281.2	Gene:	UBE2R2 / 54926	HGNCID:	19907	Length:	238	Species:	Homo sapiens

Alignment Length:	165	Identity:	62/165 - (37%)
Similarity:	94/165 - (56%)	Gaps:	24/165 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TPARRRLMRDFKRLQEDPPTGVSGAPTD-NNIMIWNAVIFGPHDTPFEDGTFKLTIEFTEEYPNK 66
            |.:::.||.:.|.|||:|..|......| :::..|...||||.:|.:|.|.||..|:|..:||..
Human     7 TSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYS 71

  Fly    67 PPTVRFVSKVFHPNVYADGGICLDIL-------------QNRWSPTYDVSAILTSIQSLLSDPNP 118
            |||.||::|::|||:|.:|.:|:.||             ..||:||.:|..||.|:.|||::||.
Human    72 PPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNT 136

  Fly   119 NSPANSTAAQLYKENR------REY----EKRVKA 143
            .||||..|:.::::.|      :||    .|:|.|
Human   137 FSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSA 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc6	NP_001246916.1	UQ_con	8..145	CDD:395127	61/160 (38%)
UBE2R2	NP_060281.2	UBCc	11..169	CDD:238117	59/157 (38%)
UBE2R2	NP_060281.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910