DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hus1-like and LTO1

DIOPT Version :10

Sequence 1:NP_477426.1 Gene:Hus1-like / 40598 FlyBaseID:FBgn0026417 Length:278 Species:Drosophila melanogaster
Sequence 2:NP_703152.1 Gene:LTO1 / 220064 HGNCID:17589 Length:137 Species:Homo sapiens


Alignment Length:124 Identity:23/124 - (18%)
Similarity:43/124 - (34%) Gaps:37/124 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 LGVSSANLGRALSVLRGGGVNS---CKLKLQRIQFPCISVIASVLTSSSTEAREVVHDVPVTIIP 143
            |||..   ||....|.|..:.|   |   .|...|....::.|..|...:...:|:..:      
Human    33 LGVME---GRQHGTLHGAKIGSEIGC---YQGFAFAWKCLLHSCTTEKDSRKMKVLESL------ 85

  Fly   144 GSDWSAYVVPRVPNSQLALGLPSLRLLKSLIDKLK----------NISPSLEFQVNVDG 192
                 ..::.:.|...     |:...|...:||::          |:.|  :|:::.:|
Human    86 -----IGMIQKFPYDD-----PTYDKLHEDLDKIRGKFKQFCSLLNVQP--DFKISAEG 132

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hus1-likeNP_477426.1 Hus1 1..276 CDD:461127 23/124 (19%)
LTO1NP_703152.1 Yae1_N 22..60 CDD:430844 10/32 (31%)
deca-GX3 motif, required for interaction with YAE1 and the CIA complex. /evidence=ECO:0000250|UniProtKB:P53846 22..58 9/30 (30%)

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