DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14655 and CG18262

DIOPT Version :9

Sequence 1:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	90/373 - (24%)
Similarity:	135/373 - (36%)	Gaps:	115/373 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 CDICEFSFRNTELRDMHVRLVHENAEG-----EPKQKEPQQKEPDQEPYKCH--LCSKTFRMKGS 171
            ||.|:.::........|.||.|..|.|     ...::..::::...:.|||:  .|::|||.:..
  Fly   174 CDQCDRAYNTKRSLQSHRRLKHSEANGGSLDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERD 238

  Fly   172 LRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICDRIRHTEPGALGNGNNSTCTA 236
            ||.|                                         |.:||
  Fly   239 LRGH-----------------------------------------RWKHT--------------- 247

  Fly   237 SQPYALSGALSMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICAR 301
                   |..                     ||:|.|.||....:.:|::.|:|..|:.|..|..
  Fly   248 -------GIF---------------------CDICGKPFTQSGNMMRHRQRHSGIKPHKCPECDA 284

  Fly   302 TFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFL 366
            ||..|:....|.:.|:...|.:|.||||..::...|..|.|.|:||:|.|||||||.|.......
  Fly   285 TFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMRRHTGERPAKCEVCGKAFYSFHDLN 349

  Fly   367 VHTRIHTGVMPYKCELCQKTFRYKVSQRTHR-------------CPTEEAQTPEQLIKAFLEGND 418
            ||...||.:.|:.|::|..||:.|.:.|.|:             |....||:..  :.|.:..:|
  Fly   350 VHAVSHTNLRPFVCDVCGSTFQRKKALRVHKLLHSEQRKYACKLCGKTFAQSGG--LNAHMRSHD 412

  Fly   419 -----SHTQPSPASAEIAAINSSSIVDPEQEALLSQSIDDIVVEQCQK 461
                 ...:|.|.|..|..|...|    .....::.:||..|.||..|
  Fly   413 PARVKGAVKPLPQSVTIEVIEGKS----PPTTTITMAIDLNVEEQLVK 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		zf-H2C2_2	281..304	CDD:290200	7/22 (32%)
		C2H2 Zn finger	324..344	CDD:275368	8/19 (42%)
		zf-H2C2_2	339..361	CDD:290200	14/21 (67%)
		C2H2 Zn finger	352..372	CDD:275368	9/19 (47%)
		zf-H2C2_2	364..389	CDD:290200	9/24 (38%)
		C2H2 Zn finger	380..396	CDD:275368	6/15 (40%)
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	9/62 (15%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		COG5048	<256..415	CDD:227381	52/160 (33%)
		zf-H2C2_2	263..288	CDD:290200	8/24 (33%)
		C2H2 Zn finger	279..327	CDD:275368	16/47 (34%)
		zf-H2C2_2	320..342	CDD:290200	14/21 (67%)
		C2H2 Zn finger	335..355	CDD:275368	9/19 (47%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		zf-C2H2	389..411	CDD:278523	4/23 (17%)
		C2H2 Zn finger	391..411	CDD:275368	4/21 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100