Protein Alignment eIF3a and EIF3A

DIOPT Version :10

• Sequence 1: NP_649470.2
• Gene: eIF3a / 40563
• FlyBaseID: FBgn0037249
• Length: 1140
• Species: Drosophila melanogaster
• Sequence 2: NP_192881.1
• Gene: EIF3A / 826746
• AraportID: AT4G11420
• Length: 987
• Species: Arabidopsis thaliana
• Alignment Length: 1110
• Identity: 365/1110 - (32%)
• Similarity: 576/1110 - (51%)
• Gaps: 175/1110 - (15%)

  Fly     1 MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKK 65
            ||.:. :||||||||:|.|.||:...||..|.::..:||  |...:..:|.:|||||.|||:||:
plant     1 MANFA-KPENALKRADELINVGQKQDALQALHDLITSKR--YRAWQKPLEKIMFKYLDLCVDLKR 62

  Fly    66 SHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPES 130
            ...||:||.|||.:.|.|||:|||.||:.:|.:|.:..|.|::|:.|....|::|||:....||.
plant    63 GRFAKDGLIQYRIVCQQVNVSSLEEVIKHFLHLATDKAEQARSQADALEEALDVDDLEADRKPED 127

  Fly   131 ILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRK 195
            :.:|.|.||..:|||||.::.||.|||||:|...||:||.|:..||||...|..|||||.:|.|.
plant   128 LQLSIVSGEKGKDRSDRELVTPWFKFLWETYRTVLEILRNNSKLEALYAMTAHKAFQFCKQYKRT 192

  Fly   196 SEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDI 260
            :||||||:.:|.||.::.|..:|.....::..|:.||.||||...|..|.::.|||||::::|||
plant   193 TEFRRLCEIIRNHLANLNKYRDQRDRPDLSAPESLQLYLDTRFDQLKVATELGLWQEAFRSVEDI 257

  Fly   261 HGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAH 325
            :|||.:.||||....:..||.||..:|..:.:.|:||.|..|||.|.:...|||::.|||.:|:.
plant   258 YGLMCMVKKTPKSSLLMVYYSKLTEIFWISSSHLYHAYAWFKLFSLQKNFNKNLSQKDLQLIASS 322

  Fly   326 VLLATLSIPLPSAHPEFDRFIEADKSPLEKAQ----KLAVLLGLPQPP--------TRVSLIREV 378
            |:||.|||      |.|||...|....||..:    ::|.|:|....|        :|.:|:.|:
plant   323 VVLAALSI------PPFDRAQSASHMELENEKERNLRMANLIGFNLEPKFEGKDMLSRSALLSEL 381

  Fly   379 VRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENG----------PENALLTPYIQS 433
            |...|....|::.::|::.||.:|:||:|..:||.:::.|...          || ..|:.|:.|
plant   382 VSKGVLSCASQEVKDLFHVLEHEFHPLDLGSKIQPLLEKISKSGGKLSSAPSLPE-VQLSQYVPS 445

  Fly   434 LKDVTIMRLIRQISQVYESIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGT 498
            |:.:..:||::|:|::|::|:.:.|.||..|....|:||:.|::|::|.:.:::||.|..:.||.
plant   446 LEKLATLRLLQQVSKIYQTIRIESLSQLVPFFQFSEVEKISVDAVKNNFVAMKVDHMKGVVIFGN 510

  Fly   499 DLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVNHYHEI 563
            ...||      ||          :|..|...:..|::..:::||  ...:.:||.. ::.:..:.
plant   511 LGIES------DG----------LRDHLAVFAESLSKVRAMLYP--VPSKASKLAG-VIPNLADT 556

  Fly   564 KDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQ 628
            .::||:|:|.|:.|||.|||..|:|....|.||.:::.:..:..:.||||||..|..||.::|..
plant   557 VEKEHKRLLARKSIIEKRKEDQERQQLEMEREEEQKRLKLQKLTEEAEQKRLAAELAERRKQRIL 621

  Fly   629 NEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKK--LDAEQIAKRE------SEELQREAK 685
            .||:   ||.|:|....:.:|.  |:|     ::|.||  ||.|::.|:.      :|:| :|.:
plant   622 REIE---EKELEEAQALLEETE--KRM-----KKGKKKPLLDGEKVTKQSVKERALTEQL-KERQ 675

  Fly   686 ELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVAQQ 750
            |::.||:...|.:||.|||||.|..||.|.....:.|:::||:|..::..:|.:....:..:.::
plant   676 EMEKKLQKLAKTMDYLERAKREEAAPLIEAAYQRRLVEEREFYEREQQREVELSKERHESDLKEK 740

  Fly   751 ERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIIRRREE-----RRQAFL 810
            .||.||..:::.|       :|.:...:..:|: .:..||::|:: :|||.:::     |:|.:.
plant   741 NRLSRMLGNKEIF-------QAQVISRRQAEFD-RIRTEREERIS-KIIREKKQERDIKRKQIYY 796

  Fly   811 REKEEERLRK---EEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDR 872
            .:.||||:||   |||.|..:.||.....||   ||:|..:|   .:||||.:|.|.|.|.:.:|
plant   797 LKIEEERIRKLQEEEEARKQEEAERLKKVEA---ERKANLDK---AFEKQRQREIELEEKSRRER 855

  Fly   873 DRLSRELASERERTEKDRDTWRPRGGDRPSASNGGSS--------EWRRAAPAASERNDRGGERI 929
            :.|.|...:...|..:  .|..|.|...|:|:...:.        :|:|
plant   856 EELLRGTNAPPARLAE--PTVTPVGTTAPAAAAAAAGAPAAPYVPKWKR---------------- 902

  Fly   930 ERGGERIERGGERLERGGERIERGGDRDRKDNEG---ADSSWRVRREPDSQRAAAPKDSGAPQSR 991
                       :..|..|.......:.||:.|.|   .|..|      .|.|.||        ..
plant   903 -----------QTTEVSGPSAPTSSETDRRSNRGPPPGDDHW------GSNRGAA--------QN 942

  Fly   992 DDKWRRGGERDRDFRIDGARRDRDDGPRRDRDDGPRRDRDDERGGFRRADGARRTDEPQRETGGN 1056
            .|:|....||                      .||..:     ||.|...|.|.:|: :|.|.|:
plant   943 TDRWTSNRER----------------------SGPPAE-----GGDRWGSGPRGSDD-RRSTFGS 979

  Fly  1057 WRDAP 1061
            .|..|
plant   980 SRPRP 984

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3a	NP_649470.2	PINT	429..>497	CDD:214509	22/67 (33%)
		PTZ00121	<553..1128	CDD:173412	146/536 (27%)
		PRK12678	847..>1006	CDD:237171	36/169 (21%)
EIF3A	NP_192881.1	PCI	<434..509	CDD:460195	25/75 (33%)
		PTZ00121	<559..841	CDD:173412	100/307 (33%)