Protein Alignment Syt14 and Syt13

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_109650.1
• Gene: Syt13 / 80976
• MGIID: 1933945
• Length: 426
• Species: Mus musculus
• Alignment Length: 451
• Identity: 101/451 - (22%)
• Similarity: 166/451 - (36%)
• Gaps: 120/451 - (26%)

  Fly   173 GVLT-----GLSKATTTV-PHPATAFRNPCGEHRAKT--QALRY-----QHRVNVAAPPKLDKER 224
            |||.     .:.|:|..| |.|...|.:..|...|.|  :.:.|     :.....|||.....:.
Mouse    54 GVLQAAQQFNIKKSTEPVQPRPLLKFPDIYGPRPAVTAPEVINYADYTLETTEESAAPASPQAQS 118

  Fly   225 DNVLVVPMVNAYSINNNNNSI------TTSNNHPSSNNND----------DE---PLFDTSDLRS 270
            |:.|...:....||...|..:      .|.|...:::.|.          |:   .||.|| |.:
Mouse   119 DSRLKRQVTEELSIRPQNGVVEDVCVMETWNPEKAASWNQAPKLHFRLDYDQKKAELFVTS-LEA 182

  Fly   271 IKSD-----DLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLP-PLGSGQTTHTQ 329
            :.||     |..:   |...||:.|.:|.:.:|      :|..:|....:.|. |||.
Mouse   183 VTSDHEGGCDCYI---QGSVAVKTGSVEAQTAL------KKRQLHTTWEEGLALPLGE------- 231

  Fly   330 VRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYV 394
                                                |::....|.:.|..|:|..:..:|||
Mouse   232 ------------------------------------EELPTATLTLTLRTCDRFSRHSVIGE--- 257

  Fly   395 SFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVT 459
                        |.|.|:..:...|.....:|.:.|:..|||:         .|:||.:||....
Mouse   258 ------------LRLGLDGASVPLGAAQWGELKTTAKEPSAGA---------GEVLLSISYLPAA 301

  Fly   460 GRLSVEIIKGSQFRSLSLNK--APDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVA 522
            .||.|.:||.....|....:  ..|..|| |.:....|::.:.:|...:.:.||::.|...|::.
Mouse   302 NRLLVVLIKAKNLHSNQSKELLGKDVSVK-VTLKHQAQKLKKKQTKRAKHKINPVWNEMIMFELP 365

  Fly   523 LFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
            ...|...::.:.|..:.....:..:|..||||::||||. :||.::.:.|: ..:|.||.|
Mouse   366 DDLLRASSVELEVLGQGEEGPSCELGHCSLGLHASGSER-SHWEEMLKNPR-RQIAMWHQL 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	19/122 (16%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	39/140 (28%)
Syt13	NP_109650.1	C2	160..277	CDD:472691	33/184 (18%)
		C2B_Synaptotagmin-13	288..425	CDD:176052	39/149 (26%)