Protein Alignment Syt14 and syt11b

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001156003.1
• Gene: syt11b / 794707
• ZFINID: ZDB-GENE-090601-7
• Length: 456
• Species: Danio rerio
• Alignment Length: 579
• Identity: 123/579 - (21%)
• Similarity: 237/579 - (40%)
• Gaps: 149/579 - (25%)

  Fly    19 EVTTLLGAFFGVLVLLLLLFLFISRKCCFHYRHAINCCDERHLAVKCVQKITRKRRYENTSSDSE 83
            :::.:|..|.|..||::.:|..|         :...||               ::.|..|:
Zfish    12 DMSPVLAGFIGAGVLVVAVFALI---------YLWTCC---------------QKHYNRTN---- 48

  Fly    84 EDILRRLRWHQQHQLGEKPGGYGLGISQANPLTAQSFNY-HQ-AGASADLQRVTVSRDPLAIAER 146
                        ::|      :|:....::|||...:.: |. .|.|.....:|.|:..:.:|..
Zfish    49 ------------YKL------HGIQSEHSDPLTDPPYKFIHMLKGMSIYPDALTNSKRIIRVARE 95

  Fly   147 GKVGIPSSHSECSSNDSMEVSVDS--HTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQ 209
            .:...............:.|::||  .:|:|                     ||.:.:.:  ...
Zfish    96 ARAQTSDRVQGSKGRPVVLVNMDSAAESGLL---------------------GEKQMRLE--ESG 137

  Fly   210 HRVNVAAPPKLDKERDNVLVVPM------VNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDL 268
            |.|:     :|::|      :|:      :::.|.:::..|.||.::..:.....|||
Zfish   138 HEVS-----RLERE------LPVRADYCCLDSSSASSSQTSSTTVSSTATPFTPADEP------- 184

  Fly   269 RSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQT--THTQVR 331
                               .||  :|.:::.|:.|.:.:.|.:::|:.||.: .|||  ....|:
Zfish   185 -------------------SRG--DLSIAIDYNFPKKALVVTILEARGLPAV-EGQTGSADPYVK 227

  Fly   332 MLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVS 395
            |.:||.||.::||:: |....|.:.|:|..:.|....::::.|...:...:|..::.:||||.|.
Zfish   228 MTILPEKKHRVKTRVLRKTLEPAFDETFTFYGVPYSSLSDLTLHFLVLSFDRFSRDDVIGEAMVP 292

  Fly   396 FATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTG 460
            .|.||               .|:|      .:.:.:..:..:...:.||   |||:.|||..|:.
Zfish   293 LAGVD---------------PSTG------RVHITQQITKRNMQCVSHG---ELLVSLSYQPVSH 333

  Fly   461 RLSVEIIKGSQFRSLSL-NKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALF 524
            ||||.::|......|.: ..:.:.|||:.:... .:.|::.||.:::...||:|.|:|.:.|...
Zfish   334 RLSVVVLKAKHLPKLDITGLSANPYVKLNVFYG-HKRIAKKKTHVKKCTLNPVFNESFIYDVPAE 397

  Fly   525 QLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
            .|.|:::...|.......||:.:|...||.:|......|||.:||:.|: ..:::||.|
Zfish   398 LLPDISIEFLVMDFDRTTKNQALGRLVLGADSPCPSGAAHWQEVCQNPR-RQISKWHTL 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	33/124 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	43/139 (31%)
syt11b	NP_001156003.1	C2	186..309	CDD:472691	37/146 (25%)
		C2B_Synaptotagmin-4	320..456	CDD:176049	44/141 (31%)