Protein Alignment Syt14 and syt3

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001186849.1
• Gene: syt3 / 779540
• XenbaseID: XB-GENE-956378
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 634
• Identity: 140/634 - (22%)
• Similarity: 241/634 - (38%)
• Gaps: 170/634 - (26%)

  Fly    17 TIEVTTLLGAFFGVLVLLLLLFLFISRKCCFHYRHAINCCDERHLAVKCVQKITRKRRYENTSSD 81
            ::.:.:::..|.|  ::||.:.||:|.|.|:                       ...|.:.:|..
 Frog    54 SVSLLSVIVTFCG--IVLLGVSLFVSWKLCW-----------------------IPWRDKGSSQT 93

  Fly    82 SEEDILRRLRWHQQHQLGEKPGGYGLGISQANPLTAQSFNYHQAGASADLQRVTVSRDPLAIAER 146
            ..:|.......|..|        ||                       ||....|...| .:.||
 Frog    94 QRKDHGHHGHLHHSH--------YG-----------------------DLLADRVELGP-EMPER 126

  Fly   147 GKVGIPSSHSECS---SNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRY 208
            ..:.: .|:.|.:   |..|.::.|||.       ....:.:|:                 |..:
 Frog   127 SYLDM-DSYPETNIKISQTSPDIPVDSQ-------PPKESQIPY-----------------AQSH 166

  Fly   209 QHRVNVA----APPKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPS-SNNNDDEPLFDTS-- 266
            |...|:|    ||.       ||....:..|...:.....:|...:.|. |.:.|::|...||
 Frog   167 QQVANIAPANVAPA-------NVAPANVAPANRYSTLPRPMTQQLSSPDFSGHVDEKPEQATSIG 224

  Fly   267 ----DLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTH 327
                :|...:|.|..:   :|:.|...|.|...|...|::  .::.|.:::|..||...:...:.
 Frog   225 QIKPELYKQRSADAEM---KKQEATSCGRISFILRYAYNS--EQLVVKILKALELPAKDANGFSD 284

  Fly   328 TQVRMLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGE 391
            ..|:|.:||.:|:|.:||: |...||.:.|:|..: |...::.|..|...:|..:|..:..|||:
 Frog   285 PYVKMYLLPDRKKKFQTKVHRKTLNPIFNETFHFN-VPFNELQNRKLHFSIYDFDRFSRHDLIGQ 348

  Fly   392 AYV------SFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELL 450
            ..:      |.||.    ||.:|               .|:|. |.||.|         .:.|:.
 Frog   349 VVLDNLLEFSNATD----ETPIW---------------RDILE-ASSEKA---------DLGEIN 384

  Fly   451 LGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKE 515
            ..|.|....|||:..|||.:..:::.|....|.|||..::.. |:.:.:.||||::...||.:.|
 Frog   385 FSLCYLPTAGRLTATIIKATNLKAMDLTGFSDPYVKASLICE-GRRLKKRKTSIKKNTLNPTYNE 448

  Fly   516 TFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNS--SGSEEVAHWADVCEMPKGEMLA 578
            ...|.:....::.|:|.|:|.....:..||::|...:|.::  .|.|   ||.::...|: :.:.
 Frog   449 ALVFDIPNENMDHVSLTIAVMDYDCIGHNEVIGMCRVGSDADMQGRE---HWNEMLANPR-KPIE 509

  Fly   579 RWHVLVDSXFEQLGQSSGRSGKALRKLSLAAFKDRSREKSSKESRLEEN 627
            .||.||:.             |||.     :|..:|.....|.|.:.:|
 Frog   510 HWHQLVEE-------------KALN-----SFMTKSPPPRDKPSIVVDN 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/128 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	38/139 (27%)
syt3	NP_001186849.1	C2A_Synaptotagmin-1-5-6-9-10	248..372	CDD:176031	36/145 (25%)
		C2B_Synaptotagmin-3-5-6-9-10	381..514	CDD:176048	38/137 (28%)