Protein Alignment Syt14 and sytl1

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001122005.1
• Gene: sytl1 / 777759
• ZFINID: ZDB-GENE-060503-439
• Length: 539
• Species: Danio rerio
• Alignment Length: 561
• Identity: 126/561 - (22%)
• Similarity: 210/561 - (37%)
• Gaps: 136/561 - (24%)

  Fly    71 RKRRYENTSSDSEEDILRRL--RW-HQQHQLGEKPGGYGLGISQANPLTAQSFNYHQAGAS---A 129
            |.|:.:.|.||...  ||.|  .| |::                      :|..|.:.||.   |
Zfish    37 RVRKLQQTVSDPVH--LRSLSGAWFHEE----------------------RSKRYEKGGADVVHA 77

  Fly   130 DLQRVTVSRD-PL-AIAERGKVGIPSSH----------SECSSNDSM-EVSVDSH-----TGVLT 176
            .|:|....:| || ||.::|.   .|||          :|.....:| |...|.|     :|...
Zfish    78 SLRRKRRGKDLPLTAIFDKGN---NSSHVHEQQEEDRNAERDLQGNMNEREDDKHQEQKESGQED 139

  Fly   177 GLSKATTTVPHPATAFRN--------PCGEHRAKTQALRYQHRVNVAAPP--KLDKERDNVLVVP 231
            |.|..:..:..|.:..||        ..|...:..::...:.|:..:..|  ::|.|.|
Zfish   140 GESLISNAITIPQSRTRNVTKRNEILGSGFEDSVEESENKERRILPSTSPTLQIDSEGD------ 198

  Fly   232 MVNAYSINNNN---NSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIE 293
             :::.|...|.   .|:|:..:|...|.             |:.|   |..|......|..|  .
Zfish   199 -IDSGSTEINYTRFGSVTSLTSHHMMNG-------------SLMS---LYSVGDFGDVVVSG--R 244

  Fly   294 LELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLP--SKKQKLKTKIRSGE-NPQYM 355
            ::.||.||....::.||:::.::|......: :...|::.:||  :.:.|.||.:|... ||.|.
Zfish   245 IQFSLQYDVRTEELYVHIIRCQDLASARKNR-SDPYVKVYLLPDNTSRSKKKTAVRRKTLNPVYD 308

  Fly   356 ESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPRNTSS-- 418
            |: :.::|...|:....|.:.::..||:|:...:||..|.....|.......|..|:||...|
Zfish   309 ET-MTYKVRRLDLPARVLSMSVWHMERMRRNLFLGELEVRLGQWDWSQNQPTWQNLQPRVQLSPE 372

  Fly   419 GLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSV---EIIKGSQFRSLSLNK- 479
            .:.|...:|...:....||..   .|           |..||.|.:   ||:      .|...|
Zfish   373 AIISRGTILFSIKFVPPGSEG---RG-----------NPATGELHIWLREIV------GLLPTKR 417

  Fly   480 -APDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKK 543
             ||:||||.|::.. ...:|..:|.:.||..:|:|..|..:..  ||.:|:....:.....:...
Zfish   418 GAPNTYVKSVVLPD-ESGVSGQQTRVVRGSVSPVFNHTMVYDG--FQSSDLIQACAEITVWNPHP 479

  Fly   544 NEMVGWFSLGLNS------------SGSEEVAHWADVCEMP 572
            :..:|...|...|            |..:|:..|:.|.:.|
Zfish   480 SGCLGGVRLSTGSGLSYGQSVCWMDSTEDEINVWSSVIQSP 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	30/124 (24%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	33/144 (23%)
sytl1	NP_001122005.1	C2A_SLP-1_2	242..364	CDD:176039	30/125 (24%)
		C2B_SLP_1-2-3-4	377..531	CDD:175987	37/167 (22%)