Protein Alignment Syt14 and Syt5

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_062223.1
• Gene: Syt5 / 54309
• RGDID: 3806
• Length: 386
• Species: Rattus norvegicus
• Alignment Length: 293
• Identity: 74/293 - (25%)
• Similarity: 140/293 - (47%)
• Gaps: 33/293 - (11%)

  Fly   294 LELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKI-RSGENPQYMES 357
            |:.||.||....::.|.::||:.|..|..|.::...|.:.:||.|:::.:||: |...||.:.|:
  Rat   112 LQYSLDYDFQTGQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGET 176

  Fly   358 FLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLW--LPLEPRNTSSGL 420
            |.. :|...::....|.:.:|..:|..:...|||..|..::|:|......|  |.:.|:.....|
  Rat   177 FAF-KVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEKL 240

  Fly   421 GSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYV 485
            |                          ::...|.|....|:|:|.:::....:.:.:....|.||
  Rat   241 G--------------------------DICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYV 279

  Fly   486 KMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWF 550
            |:.::.. |:::.:.||:|::...||.:.|.|:|:|...|:..|.:.::|.....:.|||.:|..
  Rat   280 KVHLLQG-GKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV 343

  Fly   551 SLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
            ::| .:.|...:.||||:...|: ..:|:||.|
  Rat   344 AVG-TAVGGAGLRHWADMLANPR-RPIAQWHSL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/121 (28%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	37/138 (27%)
Syt5	NP_062223.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Syt1_2_N	6..76	CDD:425364
		C2A_Synaptotagmin-1-5-6-9-10	108..230	CDD:176031	33/118 (28%)
		C2B_Synaptotagmin-1	240..374	CDD:176047	38/162 (23%)