Protein Alignment Syt14 and Tc2n

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_038968674.2
• Gene: Tc2n / 500707
• RGDID: 1563876
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 568
• Identity: 100/568 - (17%)
• Similarity: 203/568 - (35%)
• Gaps: 190/568 - (33%)

  Fly    54 NCC-------DERHLAVKCVQKITRKRRYENTSSDSEEDILRRLRWHQQHQLGEKPGGYGLGISQ 111
            :||       .|:|       |.:.::.::.::|:|:..|                     ||:|
  Rat     8 SCCRGCFYGETEKH-------KFSVEKEFKASASNSQNTI---------------------GITQ 44

  Fly   112 ANPLTAQSFNYHQAGASAD--LQRV---------TVSRDPLAIAERGKVGIPSSHSECSSNDSME 165
            ...:.|:.    |.|.:.|  |.::         .|.|..|:..:....|.|
  Rat    45 LTSVLAKP----QVGCNEDYLLSKLPCDGKEVQFVVPRFKLSYIQPRTQGTP------------- 92

  Fly   166 VSVDSHTGVLTGLSKAT---------TTVPHPAT-AFRNPCGEHRAKTQALRYQHRVNVAAPPKL 220
                ||...|.|.::|:         ::..|.:. ...|||         ..|||     ..|.|
  Rat    93 ----SHLDELEGSARASFGDQKTELCSSFYHGSIYDVYNPC---------YMYQH-----FSPDL 139

  Fly   221 DKERDNVLVVP------------------MVNAYSINNNNNSITTSNNH-----------PSSNN 256
            .:.     .:|                  :..:..::.:...:|||:..           |||::
  Rat   140 SRR-----FLPHCETKTLYGSVCDLRTSKLPGSPGLSKSMLDLTTSSQRFIQRHDSFSSVPSSSS 199

  Fly   257 NDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLP-PL 320
            :...   .....||:  |.:.:..|:::..      .|.:.|.|::...::.:.::|.:::. |.
  Rat   200 SRKN---SQGSNRSL--DTITLSGDERDLG------RLNVKLFYNSSAEQIWITILQCRDISWPS 253

  Fly   321 GSGQTTHTQVRMLMLPSKKQKLKTKIRSGENP-QYMESFLLHRVNPEDVNNMGLRVRLYGCERLR 384
            ..|.|....::.::..||....|:..:.|.|. .:||:|:             ..::|...:.:|
  Rat   254 SYGDTPTISIKGILTLSKPIHFKSSAKEGSNAIDFMETFV-------------FAIKLQNLQAVR 305

  Fly   385 ----------KERLIGEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTS 439
                      |::.|||..:|..|:..: |.:..|.:.|.:.          .|:.:
  Rat   306 LAFKIQTQTPKKKTIGECSLSLRTLSTQ-EMDYSLEIIPPSK----------FSVCQ-------- 351

  Fly   440 SMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSI 504
                   :||.||..:..|..|:.::|::.....|.|...|...:||:.|.|| |:.|.:.||.:
  Rat   352 -------AELELGTCFQAVNSRIQLQILEAQYLPSSSTPLALSFFVKVGMFSS-GELIYKKKTRL 408

  Fly   505 RRGQPNPL-FKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFS 551
            .:.....: :.||..|.:...: .::..:|.:|::..:::...||..|
  Rat   409 LKASSGRVKWGETMIFPLIQTE-KEIVFLIKLYSRSSVRRKHFVGQVS 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	25/133 (19%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	27/107 (25%)
Tc2n	XP_038968674.2	None