Protein Alignment Syt14 and syt11a

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_998625.2
• Gene: syt11a / 406769
• ZFINID: ZDB-GENE-040426-2815
• Length: 451
• Species: Danio rerio
• Alignment Length: 586
• Identity: 129/586 - (22%)
• Similarity: 229/586 - (39%)
• Gaps: 162/586 - (27%)

  Fly    17 TIEVTTLLGAFF--GVLVLLLLLFLFISRKCCFHYRHAINCCDERHLAVKCVQKITRKRRYENTS 79
            |.:|:.:|..|.  ||||:.:.:.:|:           ..||               :|||.
Zfish    10 TYDVSPVLAGFLGAGVLVVSVTVAVFL-----------WTCC---------------QRRYR--- 45

  Fly    80 SDSEEDILRRLRWHQQHQLGEKPGGYGLGISQANPLTAQSFNY-HQAGASADLQRVTVSRDPLAI 143
                                :..|.|.|.....:|.....:.: |.      |:.:::..:.|:.
Zfish    46 --------------------QMTGAYKLTSGPYDPPVDPPYKFIHM------LKGISIYPETLSN 84

  Fly   144 AER-GKVGIPSSHSE--------CSSNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEH 199
            ::: .:||..|:.:.        ..:.|.:.|..|..                        ||
Zfish    85 SKKIVRVGRRSASNSLLREWGRGSRNGDVLLVDADPE------------------------CG-- 123

  Fly   200 RAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFD 264
               |..|:..|.|....||:|::      .:|:...|....            ||:.:..|....
Zfish   124 ---TTHLQMNHLVPPVGPPRLER------ALPIRADYCCME------------SSSGSSSEAHSK 167

  Fly   265 TSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLG-SGQTTHT 328
            |:...|:.|..|  |.             |.|::.|:.|.:.:.|.::.|:.||.:. ...::..
Zfish   168 TASPYSLNSPSL--GT-------------LSLAIDYNFPKKALVVTIIGAQGLPAVDEQAGSSDP 217

  Fly   329 QVRMLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEA 392
            .|:|.:||.||.::||:: |....|.:.|:|..:.|....:..:.|...:...:|..::.:||||
Zfish   218 YVKMTILPEKKHRVKTRVLRKTLEPVFDETFTFYGVPYSSLPELTLHFLVLSFDRFARDDVIGEA 282

  Fly   393 YVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSL--ARSESAGSTSSMQHGGVSELLLGLSY 455
            .|               |||..:.|:|....:..:|.  .:.||.|           |||:.|||
Zfish   283 VV---------------PLEGVDPSTGRAHITQQISKRNTQCESRG-----------ELLVSLSY 321

  Fly   456 NGVTGRLSVEIIKGSQFRSLSL-NKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAF 519
            :.||.||:|.::|.....::.: ..:.:.||| |.|....:.|::.||.:::...||:|.|:|.:
Zfish   322 HPVTHRLNVVVLKAKHLPTMDITGLSGNPYVK-VNVFYGRKRIAKKKTHVKKCTLNPVFNESFIY 385

  Fly   520 QVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLV 584
            .|....:.|:::...|.......|||:||...||..|.....|.||.:||:.|: ..:|:||.|:
Zfish   386 DVPAELMPDISVEFLVIDFDRTTKNEVVGRLVLGGQSPIPSGVTHWREVCDNPR-RQIAKWHNLI 449

  Fly   585 D 585
            :
Zfish   450 E 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	30/123 (24%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	45/138 (33%)
syt11a	NP_998625.2	C2	179..290	CDD:472691	33/140 (24%)
		C2B_Synaptotagmin-4	312..449	CDD:176049	46/149 (31%)