Protein Alignment Syt14 and Sytalpha

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 118/522 - (22%)
• Similarity: 193/522 - (36%)
• Gaps: 116/522 - (22%)

  Fly    62 AVKCVQKITRKRRYENTSSDSEEDILRRLRWHQQHQL---GEK----------PGGYGLGISQAN 113
            ||......|..:||             ||.|.:|:.|   .||          .|..|..:...|
  Fly    38 AVGAALYTTCSKRY-------------RLNWFEQNLLESANEKDEDQQREALVAGAVGYNVDNVN 89

  Fly   114 PLTAQSFNYHQAGASADLQRVTVSRDPLAIAERGKVGIPSSHSECSSNDSMEVSVDSHTGVLTGL 178
            .:....::...||..:.....:...||       ...:|:|   .:|..:::..|.:
  Fly    90 EVPRGKYSSGNAGNLSPTSLKSEDNDP-------AFWVPAS---VTSTAAIQQQVSN-------- 136

  Fly   179 SKATTTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAYSINNNNN 243
               ||....|.|   :|.|.  .|:..|.|....:|   |....::..||.:
  Fly   137 ---TTEESAPPT---SPTGS--LKSNTLSYCSTTSV---PIARSDKHVVLAM------------- 177

  Fly   244 SITTSNNHP------SSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDA 302
                   ||      |.|...|....|.:..||......:..|...|   .||  .|.:||.||.
  Fly   178 -------HPSRPRVSSMNAKLDHTKIDMTLYRSHSQPKTINPVSLNE---VRG--NLHVSLGYDP 230

  Fly   303 PMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKIRSGE-NPQYMESFLLHRVNPE 366
            ....:.|.:::|:||.|.....|.....::.:||.||...:|:|.... ||.:.|.|:. .|...
  Fly   231 VGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVF-EVTAG 294

  Fly   367 DVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLAR 431
            .::...:.:.||..:...:...||.:.:..|.:||..:..||.||
  Fly   295 VIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPL-------------------- 339

  Fly   432 SESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSL-SLNKAPDTYVKMVMVSSIGQ 495
              |:.|...|: ..:.::::.|:|.....||.|.:||....|.: ....:.|.|||:.::...|:
  Fly   340 --SSASAQDMK-VDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGK 401

  Fly   496 EISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSE 560
            :|.:.||.::||..||::.|..||.||...|.:..|..:|.....:..:|::|...:|    .|.
  Fly   402 KIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIG----NSP 462

  Fly   561 EV 562
            ||
  Fly   463 EV 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	33/122 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	34/118 (29%)
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	35/147 (24%)
		C2B_Synaptotagmin	352..488	CDD:175975	34/117 (29%)