Protein Alignment Syt14 and Sytl1

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001385966.1
• Gene: Sytl1 / 297872
• RGDID: 1310715
• Length: 562
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 136/571 - (23%)
• Similarity: 216/571 - (37%)
• Gaps: 121/571 - (21%)

  Fly    78 TSSDSE--EDILRR---LRWHQQHQLGEKPGGYGLGISQANP-----LT------AQSFNYHQAG 126
            |..:.|  .|:|:|   ||..::.::.:      |..|.|:|     ||      |:|..:|.|.
  Rat    38 TEEEQEAISDVLKRDAHLRQLEEGRVSK------LRASLADPWQLKILTGDWFQEARSQRHHHAH 96

  Fly   127 ASADLQRVTVSR---------------------DPLAIAERG---KVGIPSSHSECSSNDSMEVS 167
            ..:||.|.::.|                     |.:..||..   ||..|.:|:|....|.
  Rat    97 FGSDLVRASIRRKKSSKGDQALGSDGDGEAAGEDTIEEAEPRVSIKVAAPETHTETQEPDF---- 157

  Fly   168 VDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQHRVNVA-APPKLDKERD---NVL 228
              |...|||.:|..                |...:.|....|..|.|| |.|:||.|::   ...
  Rat   158 --SSPYVLTKVSSQ----------------EEEPQDQEAPGQGGVQVAEADPELDPEQEAEQESW 204

  Fly   229 VVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIE 293
            ..|.    .|...:..:......|....:.|..|..:|.:.|:.|..|...:.......:.||::
  Rat   205 PTPA----QIKTTSKVLENGEETPGLGPSLDRMLSSSSSVSSLNSSTLSGSLKSLSGEAEAGPVQ 265

  Fly   294 LE----LSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKIRSGE-NPQ 353
            :.    .||.|:....::.|.|:|.:.| .....:.:...|:..:||.|:.|.||.::... ||.
  Rat   266 VRGSVLFSLRYEPGTGELRVQVIQCQGL-AAARRRRSDPYVKSYLLPDKQNKRKTSVKKRNLNPI 329

  Fly   354 YMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPR-NTS 417
            :.|: |.|.|...|:....|.:.::..|.|.:...:||..|...|.:.:.|.. ||||:|| .||
  Rat   330 FNET-LRHSVQQADLPGRVLSLSVWHRESLGRNIFLGEVEVPLDTWNWDSEAT-WLPLQPRIPTS 392

  Fly   418 SGLGSTSDLLSL------ARSESAGSTSSMQ-HGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSL 475
            .....:..||||      |.||..|...|.: |..:.| ..||          |.:..||.
  Rat   393 PDELPSRGLLSLSLKYIPAGSEGGGQPPSGELHFWIKE-AQGL----------VPLRPGSL---- 442

  Fly   476 SLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQ-VALFQLNDVTLMISVYAKR 539
                  |||::..::.. ....||.:|.:.|...:|:|..|..:. .....|......:|::...
  Rat   443 ------DTYIQCSVLPD-DSRASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHG 500

  Fly   540 HMKKNEMVGW-FSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLVDSXFE 589
            .:...::.|. .|||..||...:|. |.|  ..|:.:.|  |..|::...|
  Rat   501 ALASRQLGGTRLSLGTGSSYGLQVP-WMD--STPEEKQL--WQTLLEQPCE 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/126 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	30/139 (22%)
Sytl1	NP_001385966.1	PHD_SF	35..>90	CDD:473978	14/57 (25%)
		C2	267..386	CDD:472691	32/121 (26%)
		C2B_SLP_1-2-3-4	399..555	CDD:175987	42/175 (24%)