DRSC/TRiP Functional Genomics Resources

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Protein Alignment Syt14 and SYT14

DIOPT Version :10

Sequence 1:NP_001262249.1 Gene:Syt14 / 40544 FlyBaseID:FBgn0261086 Length:648 Species:Drosophila melanogaster
Sequence 2:XP_006711325.1 Gene:SYT14 / 255928 HGNCID:23143 Length:864 Species:Homo sapiens


Alignment Length:349 Identity:145/349 - (41%)
Similarity:212/349 - (60%) Gaps:22/349 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 NDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLG 321
            :|...:....|:.:..|...|......||..:.|  .|:::..||:..:|:.|.|....::|...
Human   519 SDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG--TLDVTFDYDSQEQKLLVTVTAVTDIPTYN 581

  Fly   322 SGQTTHTQVRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKE 386
            .......||.:::||.|||:.||.|:.|..|.:.|:|..:.|..|.:.|..:|.||||..|::||
Human   582 RTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKE 646

  Fly   387 RLIGEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLL 451
            :::||.......::|:.:.:|.:.|||....||..|...:..::.|||..|..|::||.|.|:|:
Human   647 KIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILI 711

  Fly   452 GLSYNGVTGRLSVEIIKGSQFRSLSLNKAP-------------------DTYVKMVMVSSIGQEI 497
            ||.||..|||||.|:||||.|::|:.|:.|                   |||||:.:::|:|||:
Human   712 GLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEM 776

  Fly   498 SRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEV 562
            |:.|||||||||||::||||.||||||||:||||::|||.||.||:.||:||.||||||||.||:
Human   777 SKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEEL 841

  Fly   563 AHWADVCEMPKGEMLARWHVLVDS 586
            .||.::.| .||:.:.|||.|::|
Human   842 NHWTEMKE-SKGQQVCRWHALLES 864

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syt14NP_001262249.1 C2A_Synaptotagmin-14_16 291..413 CDD:176035 37/121 (31%)
C2B_Synaptotagmin-14_16 446..584 CDD:176053 87/156 (56%)
SYT14XP_006711325.1 C2A_Synaptotagmin-14_16 550..673 CDD:176035 38/124 (31%)
C2B_Synaptotagmin-14_16 706..862 CDD:176053 87/156 (56%)

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