Protein Alignment Syt14 and SYT11

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_016856248.1
• Gene: SYT11 / 23208
• HGNCID: 19239
• Length: 434
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 92/391 - (23%)
• Similarity: 174/391 - (44%)
• Gaps: 74/391 - (18%)

  Fly   212 VNVAAPPKLDKERD----------NVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTS 266
            |:.|....|.:::|          :.|.:.|.....:.:...|:|...:..:|.::.:|
Human    96 VDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPEE------ 154

  Fly   267 DLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPL-GSGQTTHTQV 330
                    |:::|             .|..|:.|:.|.:.:.|.:.:|..||.: ...|.:...:
Human   155 --------DVMLG-------------SLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYI 198

  Fly   331 RMLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYV 394
            :|.:||.|:.::||:: |...:|.:.|:|..:.:....:.::.|...:...:|..::.:|||..|
Human   199 KMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMV 263

  Fly   395 SFATVDLELETNLWLPLEPRNTSSG-LGSTSDLL--SLARSESAGSTSSMQHGGVSELLLGLSYN 456
            ..|.||               .|:| :..|.|::  ::.:..|.|           ||.:.|||.
Human   264 PLAGVD---------------PSTGKVQLTRDIIKRNIQKCISRG-----------ELQVSLSYQ 302

  Fly   457 GVTGRLSVEIIKGSQFRSLSL----NKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETF 517
            .|..|::|.::|......:.:    .:|||.||| |.|....:.|::.||.:::...||:|.|:|
Human   303 PVAQRMTVVVLKARHLPKMDITGLSGRAPDPYVK-VNVYYGRKRIAKKKTHVKKCTLNPIFNESF 366

  Fly   518 AFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHV 582
            .:.:....|.|:::...|.......|||:||...||.:|..:....||.:|||.|: :.:|:||.
Human   367 IYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPR-KPVAKWHS 430

  Fly   583 L 583
            |
Human   431 L 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	28/123 (23%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	46/142 (32%)
SYT11	XP_016856248.1	C2A_Synaptotagmin-4-11	158..283	CDD:176034	33/152 (22%)
		C2B_Synaptotagmin-4	292..432	CDD:176049	47/153 (31%)