Protein Alignment Syt14 and Syt4

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_321260.4
• Gene: Syt4 / 1281315
• VectorBaseID: AGAMI1_010967
• Length: 480
• Species: Anopheles gambiae
• Alignment Length: 463
• Identity: 103/463 - (22%)
• Similarity: 184/463 - (39%)
• Gaps: 113/463 - (24%)

  Fly   186 PHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPK-LDKERDNVLVVPM----------------- 232
            |.|..|.|:|.|:                  ||: |.|......:.|:
Mosquito    64 PRPPKAVRSPSGQ------------------PPQYLKKSPSPTSIKPLPGHLPAQSPTDQTTAAG 110

  Fly   233 --VNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAV-------- 287
              ..|.:......:.||::..|.:...::..|...:.....||.|:   .:..:|:.
Mosquito   111 GTTAATATTTLATTTTTTSIVPPTKYTEENELIPKNAQLEPKSPDV---SELGDPSACENGDGTE 172

  Fly   288 --QRGPIELELSLLYDAPMRKMTVHVMQAKNLP------------PLGSG-----------QT-T 326
              :.|.|..:|..|.|  ...:.|.|::.:.||            .:|.|           || |
Mosquito   173 HGKLGTIVFKLRFLAD--RSALVVSVVRCRGLPGKNHGTAAAELSTIGGGTMLCNGSANGKQTAT 235

  Fly   327 HTQVRMLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIG 390
            ...|::.:||.|:.|:||:: |:..||.|.|.|..:.:...::..|.|...:...:|..::.:||
Mosquito   236 DPYVKLQLLPDKQHKVKTRVLRNTRNPVYDEDFTFYGLTLSELAGMSLHFVVLSFDRYSRDDVIG 300

  Fly   391 EAYVSFATVDLELETN----LWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLL 451
            |.....:.:||:...|    |...::||:..            .|::..|           |||:
Mosquito   301 EVVCPLSGIDLQQIENQQVALSREIQPRSLK------------IRAQGRG-----------ELLI 342

  Fly   452 GLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKET 516
            .|.:.....||:|.::|......:.:....|.|||:.::.: ||.|::.||.:::...:|:|.|:
Mosquito   343 SLCWQPAAARLTVVLLKARNLPRMDVTGLADPYVKIYLLYN-GQRIAKKKTHVKKRTLSPVFNES 406

  Fly   517 FAFQVALFQ------LNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGE 575
            |||.:...:      |:.|:|.:.:.....:.|||::|...||...|....:.||.:||..|: .
Mosquito   407 FAFDIPTTEGAGGATLDGVSLELMLLDWDRVTKNEVIGRLELGGPRSNGSALNHWKEVCNSPR-R 470

  Fly   576 MLARWHVL 583
            .:|.||.|
Mosquito   471 QIADWHKL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	36/150 (24%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	42/144 (29%)
Syt4	XP_321260.4	C2A_Synaptotagmin-4-11	175..327	CDD:176034	37/153 (24%)
		C2B_Synaptotagmin-4	337..479	CDD:176049	43/155 (28%)