Protein Alignment MP1 and Klk5

DIOPT Version :10

• Sequence 1: NP_001303421.1
• Gene: MP1 / 40541
• FlyBaseID: FBgn0027930
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_081082.1
• Gene: Klk5 / 68668
• MGIID: 1915918
• Length: 293
• Species: Mus musculus
• Alignment Length: 294
• Identity: 86/294 - (29%)
• Similarity: 141/294 - (47%)
• Gaps: 51/294 - (17%)

  Fly   116 TKRSGT-KLLPMAPNCGE----NFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINH 175
            |:.||| :.|......||    :...|:|.|::..|...||...: ...|..:   :||..||:.
Mouse    41 TEPSGTNRDLSTDSKSGEDTRSDSSSRIVNGSDCQKDAQPWQGAL-LLGPNKL---YCGAVLISP 101

  Fly   176 RYVLTAAHCVSAIPSDWELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQY-- 238
            :::||||||...:      ..:|||....|     .|.::|::       .:...:.||||.|
Mouse   102 QWLLTAAHCRKPV------FRIRLGHHSMS-----PVYESGQQ-------MFQGIKSIPHPGYSH 148

  Fly   239 PGNSRDQLNDIALLRLRDEVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKL 303
            ||:|    ||:.|:::..:::.|..:.||.:....:..     |.:.:|:|||.|.::..:..|:
Mouse   149 PGHS----NDLMLIKMNRKIRDSHSVKPVEIACDCATE-----GTRCMVSGWGTTSSSHNNFPKV 204

  Fly   304 KAELDTVPTSE--CNQRYATQRRTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAG 366
            ...|:....||  |...|..|   :.....|||..||.|||:||||||::    .||.    :.|
Mouse   205 LQCLNITVLSEERCKNSYPGQ---IDKTMFCAGDEEGRDSCQGDSGGPVV----CNGK----LQG 258

  Fly   367 VVSYGPTPCGLKGWPGVYTRVEAYLNWIENNVRA 400
            :||:|..||..:..|||||.:..::.||::.:.:
Mouse   259 LVSWGDFPCAQRNRPGVYTNLCEFVKWIKDTMNS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:463440
		Tryp_SPc	138..397	CDD:238113	78/262 (30%)
Klk5	NP_081082.1	Tryp_SPc	67..286	CDD:214473	77/260 (30%)