Protein Alignment Trxr-2 and dld-1

DIOPT Version :9

• Sequence 1: NP_524216.1
• Gene: Trxr-2 / 40475
• FlyBaseID: FBgn0037170
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001255810.1
• Gene: dld-1 / 178387
• WormBaseID: WBGene00010794
• Length: 495
• Species: Caenorhabditis elegans
• Alignment Length: 501
• Identity: 140/501 - (27%)
• Similarity: 230/501 - (45%)
• Gaps: 64/501 - (12%)

  Fly    32 DYDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGTKWGIGGTCVNVGCIPKK-LMHQASL 95
            |.||||:|||..|...|.:||..|.:.:|        |.....:||||:||||||.| |::.:..
 Worm    29 DADLVVIGGGPGGYVAAIKAAQLGMKTVC--------VEKNATLGGTCLNVGCIPSKALLNNSHY 85

  Fly    96 LGEAVHEAVAYGWNVDDT---NIRPDWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYVNSMATFRD 157
            |..|.|:..|.|  :|.|   |:    .|::.:..|.:|.:....:...:..||.:|...||...
 Worm    86 LHMAQHDFAARG--IDCTASLNL----PKMMEAKSNSVKQLTGGIKQLFKANKVGHVEGFATIVG 144

  Fly   158 SHTIEYVAMPGAEHRQVTSEYVVVAVGGR-PRYPDIPGAVELGITSDDIFSYEREPGRTLVVGAG 221
            .:|::.....|:. ..:.:..:::|.|.. ..:|.|....:..::|....|..:.|.:.:|:|||
 Worm   145 PNTVQAKKNDGSV-ETINARNILIASGSEVTPFPGITIDEKQIVSSTGALSLGQVPKKMVVIGAG 208

  Fly   222 YVGLECACFLKGLGYEPTVM--VRSIVLRGFDRQMSELLAAMMTERGIPFL-----------GTT 273
            .:|||.....:.||.|.|.:  :..:...|.|.::|:.....:|::|..||           |:|
 Worm   209 VIGLELGSVWQRLGAEVTAVEFLGHVGGMGIDGEVSKNFQRSLTKQGFKFLLNTKVMGASQNGST 273

  Fly   274 IPKAVERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHD-DKIVVDA 337
            |...||...||      :..|.:.      ||:|.::||:...|.|.|....:...: .::.|:.
 Worm   274 ITVEVEGAKDG------KKQTLEC------DTLLVSVGRRPYTEGLGLSNVQIDLDNRGRVPVNE 326

  Fly   338 AEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMDYADVATTVFTPLEYSCVGM 402
            ...|.||.|||:||:|.| |.|...|...|.|....: ||....:||..|.:.|:|..|.:.||.
 Worm   327 RFQTKVPSIFAIGDVIEG-PMLAHKAEDEGILCVEGI-AGGPVHIDYNCVPSVVYTHPEVAWVGK 389

  Fly   403 SEETAIELRGADNIEVFHGYYKPTEF-FIPQKSVR-----HCYLKAVAEVSGDQKILGLHYIGPV 461
            :|| .::..|.        .||..:| |:.....:     ..::|.:|:...| ::||:|.|||.
 Worm   390 AEE-QLKQEGV--------AYKIGKFPFVANSRAKTNNDQEGFVKVLADKQTD-RMLGVHIIGPN 444

  Fly   462 AGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGR 507
            |||:|.....|::.|.:.:.:......|||.:|.|...::....|:
 Worm   445 AGEMIAEATLAMEYGASAEDVARVCHPHPTLSEAFREANLAAYCGK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr-2	NP_524216.1	NADB_Rossmann	29..>68	CDD:304358	14/35 (40%)
		TGR	31..515	CDD:273624	140/501 (28%)
		NADB_Rossmann	<144..239	CDD:304358	24/95 (25%)
		Pyr_redox	214..288	CDD:278498	25/86 (29%)
		Pyr_redox_dim	388..497	CDD:280934	31/114 (27%)
dld-1	NP_001255810.1	PRK06327	27..486	CDD:235779	139/495 (28%)
		NADB_Rossmann	29..>66	CDD:304358	15/44 (34%)
		Pyr_redox	201..279	CDD:278498	21/77 (27%)
		Pyr_redox_dim	375..481	CDD:280934	32/115 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920