Protein Alignment Trxr2 and gsr-1

DIOPT Version :9

• Sequence 1: NP_524216.1
• Gene: Trxr2 / 40475
• FlyBaseID: FBgn0037170
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001021220.1
• Gene: gsr-1 / 175467
• WormBaseID: WBGene00008117
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 189/500 - (37%)
• Similarity: 277/500 - (55%)
• Gaps: 45/500 - (9%)

  Fly    22 CRLAASRPRY----DYDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGTKWGIGGTCVNV 82
            |.|:.||...    ::|.:|:||||.|:|.|:.|...|..|...:..:         :|||||||
 Worm     6 CILSTSRSIMSGVKEFDYLVIGGGSGGIASARRAREFGVSVGLIESGR---------LGGTCVNV 61

  Fly    83 GCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNIRPDWRKLVRSVQNHIKSVNWVTRVDLRDKKVE 147
            ||:|||:|:..||..|.:.:...||::|  |..:.||:.:.:|...:||.:|.:....|:...||
 Worm    62 GCVPKKVMYNCSLHAEFIRDHADYGFDV--TLNKFDWKVIKKSRDEYIKRLNGLYESGLKGSSVE 124

  Fly   148 YVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAVELGITSDDIFSYEREP 212
            |:...|||.:..|:|   :.||::|   .:..::||||:|..|:|.|| |.||.||..|..|..|
 Worm   125 YIRGRATFAEDGTVE---VNGAKYR---GKNTLIAVGGKPTIPNIKGA-EHGIDSDGFFDLEDLP 182

  Fly   213 GRTLVVGAGYVGLECACFLKGLGYEPTVMVR-SIVLRGFDRQMSELLAAMMTERGIPF---LGTT 273
            .||:||||||:.:|.|..|..||.:..:::| ..|||.||:.:|:.|.|.|.|...|.   ..|.
 Worm   183 SRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQ 247

  Fly   274 IPKAVERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHDDK---IVV 335
            :.:.::.. ||.|.::   |||.:  .:...|::|||||..|.::|||:..||||  ||   |:|
 Worm   248 VTEVIKGD-DGLLTIK---TTTGV--IEKVQTLIWAIGRDPLTKELNLERVGVKT--DKSGHIIV 304

  Fly   336 DAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGST-QLMDYADVATTVFTPLEYSC 399
            |..:.||.|.|.:|||.. |:..||||||.:||.|:.|||.|.| ..:.|.::||.||:......
 Worm   305 DEYQNTSAPGILSVGDDT-GKFLLTPVAIAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGT 368

  Fly   400 VGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGDQKILGLHYIGPVAGE 464
            ||::|..|:|..|.|.:.::...:.|..|.: .|......:|.|. |..|:|::|:|..|..:.|
 Worm   369 VGLTEAEAVEKYGKDEVTLYKSRFNPMLFAV-TKHKEKAAMKLVC-VGKDEKVVGVHVFGVGSDE 431

  Fly   465 VIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDP 509
            ::||||.|:..|.|.|....||.||||:|||.    :|.|.|..|
 Worm   432 MLQGFAVAVTMGATKKQFDQTVAIHPTSAEEL----VTMRGGVKP 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr2	NP_524216.1	TGR	31..515	CDD:273624	184/490 (38%)
gsr-1	NP_001021220.1	Pyr_redox_2	19..467	CDD:476868	182/480 (38%)