Protein Alignment Trxr2 and txnrd1

DIOPT Version :10

• Sequence 1: NP_524216.1
• Gene: Trxr2 / 40475
• FlyBaseID: FBgn0037170
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001243400.1
• Gene: txnrd1 / 100495372
• XenbaseID: XB-GENE-956002
• Length: 653
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 248/516 - (48%)
• Similarity: 331/516 - (64%)
• Gaps: 14/516 - (2%)

  Fly     7 LRSSTHNALRSSLGWCRLAASRPRYDYDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGT 71
            |:.|..|..:..|........|..|||||:|:||||.|||.:||||..|.:||..|:|.|||:||
 Frog   142 LKLSKENLFQKLLETKEDNPDRSGYDYDLIVIGGGSGGLAASKEAANYGKKVLVLDFVTPTPLGT 206

  Fly    72 KWGIGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNIRPDWRKLVRSVQNHIKSVNWV 136
            |||:||||||||||||||||||:||.:|:.::..|||.::| ||:.:|..:..||.|:|.|:|:.
 Frog   207 KWGLGGTCVNVGCIPKKLMHQAALLRQALKDSQKYGWQIED-NIQHNWEIMTDSVLNYIGSLNFN 270

  Fly   137 TRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAVELGIT 201
            .||.|....|:|.|....|.:.|||:.....|.| :..|:|..::|.|.||||..|||..|..||
 Frog   271 YRVSLMQNNVKYENGYGEFVEPHTIKSTNSRGKE-KYFTAEKFLIATGERPRYLGIPGDKEYCIT 334

  Fly   202 SDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSELLAAMMTERG 266
            |||:||....||:||||||.||.||||.||.|||.:.|||||||:|||||:||:.::...|.|.|
 Frog   335 SDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMANMIGEYMEEHG 399

  Fly   267 IPFLGTTIP---KAVERQADGRLLVRYRNTTTQMDGSDV---FDTVLWAIGRKGLIEDLNLDAAG 325
            :.|:...:|   :.:|....|||.|    |:...||::.   ::|||.||||.....::.|:..|
 Frog   400 VKFIKQCVPTKIEQIEAGTPGRLKV----TSQASDGAETTEEYNTVLLAIGRDACTRNIGLEIPG 460

  Fly   326 VKTHD--DKIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMDYADVA 388
            ||.::  .||.|:..|.|:||:|:|:||::..:.|||||||.:||||||||:..||...||.:|.
 Frog   461 VKINEKTGKIPVNDEEQTNVPYIYAIGDVLQDKLELTPVAIQAGRLLARRLYGDSTVKCDYVNVP 525

  Fly   389 TTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGDQKIL 453
            |||||||||...|:|||.||.....:||||:|.|:.|.|:.:|.:....||.|.:..:....:::
 Frog   526 TTVFTPLEYGACGLSEEHAIRQYEEENIEVYHSYFWPLEWTVPARDNNKCYAKIICNLKDKGRVV 590

  Fly   454 GLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDPTPASC 514
            |.|.:.|.|||:.||||.|:|.|||...|.||:||||..||.||.|::|||||.:...:.|
 Frog   591 GFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEIFTTLTVTKRSGGNILQSGC 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr2	NP_524216.1	TGR	31..515	CDD:273624	243/492 (49%)
txnrd1	NP_001243400.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	73..153	CDD:469754	3/10 (30%)
		TGR	166..653	CDD:273624	243/492 (49%)