DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srpk79D and CG42366

DIOPT Version :9

Sequence 1:	NP_001246881.1	Gene:	Srpk79D / 40461	FlyBaseID:	FBgn0025702	Length:	1018	Species:	Drosophila melanogaster
Sequence 2:	NP_723501.2	Gene:	CG42366 / 34319	FlyBaseID:	FBgn0259712	Length:	706	Species:	Drosophila melanogaster

Alignment Length:	749	Identity:	145/749 - (19%)
Similarity:	252/749 - (33%)	Gaps:	227/749 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 NRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAAD--EIRLLEAIRDADPMDVK 407
            ||:..:.:||.|.:.||.|.:.....:.||:|.:|...:..|.|.:  |::.|:.:  :.|..||
  Fly     2 NRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKL--SHPNIVK 64

  Fly   408 RERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQVLEGLDYLHS 472
            .:.::|  .:.|:        ..|||.:..:||::| |:....|...::::|:.|||.||.::|
  Fly    65 LKEVIR--ENDTL--------YFVFEYMKENLYQMI-KDRDTHLPEPELKSILFQVLTGLAFMH- 117

  Fly   473 KCSIIHTDIKPENILL------------------------------------VIDNAAAMNQQID 501
            :....|.|:||||:|.                                    |:.::......||
  Fly   118 RHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTID 182

  Fly   502 ---------------------DEINSL----RVKGV----DFPDSY-----------------IS 520
                                 .|::.|    .|.|.    |:||.|                 :|
  Fly   183 LWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLS 247

  Fly   521 SI---------------------EKQTKSRA-KWPL------IEPNGSTNTNTN-TSNSTATNSN 556
            |:                     ::.|..:: |:|.      |.|..:|..|.. .|...|:|.:
  Fly   248 SVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRLNSKYAASNGH 312

  Fly   557 SSTPLAAVIMSTLDKEDTTT----TTSSTLNSNT----TSSLASKYSSLLGDSECNGGLGGSANI 613
            ....::..::...:|....|    .|::.:||::    .::||.|          |||      :
  Fly   313 PVQSVSNNVLPVQEKLQAVTELLHQTNNNMNSHSNLGKNNNLAPK----------NGG------V 361

  Fly   614 NNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPTDLDPEPELDSKPNTVPE------- 671
            ..:|:.:......|.......|:|.:|...:|:        |..|.|:..:...::.:
  Fly   362 PRKYQPKLSFLTTSEMGAGSHADSSSLVGGATV--------DGVPVPQHQNGGESINDIYLNRNI 418

  Fly   672 ------PSEGPIPEQPT----PNSTNSSCPSHNTATIAKSKINSNILS--TCTSLTSTNEYCFTN 724
                  |: ||..:|..    ||.:.|:..|.|...|   .:|.:.||  |.......|......
  Fly   419 SQLFGLPA-GPQHQQQQQVHHPNVSFSTTSSRNAGAI---YVNGSHLSYDTANMNAKNNAKFVVG 479

  Fly   725 TNTTTASTPSAPPSATPSSAPAL-------ASATPPSTCTPSFTQIAPS-ATAPATSTTCTTSAE 781
            .:......|.|.||.....|...       ||..|||..... .|:.|. |.||...:..:.:|.
  Fly   480 ASNGGYYVPVARPSLLGPDAKVYNVFSKVSASQAPPSLIVRQ-PQLQPEVAPAPMRLSGRSRAAA 543

  Fly   782 FYDGDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNV------------------HANAIPSQ 828
            ... |.|..:..:......:.|...|:|..... ||.|:                  :.:.:|..
  Fly   544 AVQ-DPKMGALKSDDLDLILGSKLKTSAKRQRN-AKANILLEDLFGQLSMDSDSDGKYPHTVPPT 606

  Fly   829 NQSQSSQNNT-----------YTIQSLIDNSNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVL 882
            .|::|.:.:|           ...:|.:....:|.|.........:..|........|.....|.
  Fly   607 QQAKSGKTSTGGHGAGARERDLFGESYLPRPGLRKKATQSSLEVNNGSHADSLAPNAQKEKPAVA 671

  Fly   883 LGAPY---NYTADIWSTACLAFELATGDYLFDPH 913
            ...|:   |.|.|...||.:..|  .|:.:.|.|
  Fly   672 SSFPWDESNRTEDEKLTAWMVAE--NGNLILDNH 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	STKc_SRPK	336..>504	CDD:271038	46/217 (21%)
		S_TKc	347..>492	CDD:214567	42/182 (23%)
		STKc_SRPK	<844..1012	CDD:271038	15/73 (21%)
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	57/293 (19%)
CG42366	NP_723501.2	S_TKc	4..284	CDD:214567	57/293 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24055
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100