Protein Alignment Srpk79D and Srpk2

DIOPT Version :10

• Sequence 1: NP_001246881.1
• Gene: Srpk79D / 40461
• FlyBaseID: FBgn0025702
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_038963154.1
• Gene: Srpk2 / 296753
• RGDID: 1305107
• Length: 749
• Species: Rattus norvegicus
• Alignment Length: 789
• Identity: 301/789 - (38%)
• Similarity: 409/789 - (51%)
• Gaps: 125/789 - (15%)

  Fly   270 LSLSLSPPLNRRRDMPALRGPFV-SLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGG 333
            :|::.....:..|..|..:.|.| ....|.......|.:.|:..:..|...||||||.:.||:||
  Rat    38 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPVPPEPEEEILGSDDEEQEDPADYCKGG 102

  Fly   334 YHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAI 398
            ||||.|||:|:.|:.|:||||||||||||||.|::.:::||:||||||.||.|||.|||:||:.:
  Rat   103 YHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCV 167

  Fly   399 RDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQV 463
            |::||.|..::.:|:|::.|.:.|:||:|.|:|||.||..|.|.|:|:|||||.:..|::|||||
  Rat   168 RESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQV 232

  Fly   464 LEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKS 528
            |:|||||||||.||||||||||||:.:|.|..  :::..|....:..|...|.....|...|.|
  Rat   233 LQGLDYLHSKCKIIHTDIKPENILMCVDGAYV--RRMAAEATEWQKAGAPPPSGSAVSTAPQQK- 294

  Fly   529 RAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLD--KEDTTTTTSSTLNSNTTSSLA 591
                    |.|..:.|............     |.::...|.  :|.........|..||||:.|
  Rat   295 --------PIGKISKNKKKKLKKKQKRQ-----AELLEKRLQEIEELEREAERKILEENTTSAEA 346

  Fly   592 SKYSSLLGDSECNGGLG-GSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPTD 655
            |...    |.||...:. ..|.:.:   |.::.|||.:|:.::..|.:...:::|     :...|
  Rat   347 SSEQ----DGECQPEVKLKEAELED---TTEEETAKDNGEVEDQEEKEDTEKENT-----EKDED 399

  Fly   656 LDPEPELDSKPNTVPEPSEGP-----------IPEQPTPNSTNSSCPSHNTATIAKSKINSNILS 709
             |.|.||:   |..|...|.|           :.||...:..:......|.......:.|:.
  Rat   400 -DVEQELE---NIDPTWMESPKANGHIENGLFLLEQQLEDEEDEEDDCANPEEYNLDEPNAE--- 457

  Fly   710 TCTSLTSTNEYCFTNTNTTTASTPSAPPSATPSSAPALASATPPSTCTPSFTQIAPSATAPATST 774
              :..|.::.|...|....... |.:|...||..:..|......|..:.......|..::|:...
  Rat   458 --SDYTYSSSYEQFNGELPNGQ-PKSPEFPTPLFSGPLEPVASDSVLSEGSPLTEPEESSPSRDR 519

  Fly   775 TCTTSAEFYDGDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNVHANAIPSQNQSQSSQNNTY 839
            :.|.||                      |:|.....|.|..|.|.|  |.:..||..:
  Rat   520 SRTVSA----------------------SSTGDLPKTKTRAADLLV--NPLDPQNADK------- 553

  Fly   840 TIQSLIDNSNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELA 904
                      :|||||||||||:.:.|||||||||||||||||:||.|:..||||||||:|||||
  Rat   554 ----------IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELA 608

  Fly   905 TGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQ-------------------SVIFR-------- 942
            ||||||:||:||.|||||||:|||:|||||||:                   ::|..
  Rat   609 TGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRK 673

  Fly   943 ----GKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSDFLLPMLEYNPVIRASA 1003
                ||:..::||..|.||:|||||||||.:||||||.|...:|.:|:|||:||||..|..||||
  Rat   674 YAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASA 738

  Fly  1004 AECLQHPWL 1012
            .|||:||||
  Rat   739 GECLRHPWL 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	Protein Kinases, catalytic domain	336..>504	CDD:473864	97/167 (58%)
		PHA03307	627..>759	CDD:223039	25/142 (18%)
		Protein Kinases, catalytic domain	<844..1012	CDD:473864	114/198 (58%)
Srpk2	XP_038963154.1	Protein Kinases, catalytic domain	103..>291	CDD:473864	103/189 (54%)
		2A1904	<338..417	CDD:273344	25/94 (27%)
		Protein Kinases, catalytic domain	<538..747	CDD:473864	120/227 (53%)