DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Srpk79D and Srpk2

DIOPT Version :9

Sequence 1:	NP_001246881.1	Gene:	Srpk79D / 40461	FlyBaseID:	FBgn0025702	Length:	1018	Species:	Drosophila melanogaster
Sequence 2:	XP_038963154.1	Gene:	Srpk2 / 296753	RGDID:	1305107	Length:	749	Species:	Rattus norvegicus

Alignment Length:	789	Identity:	301/789 - (38%)
Similarity:	409/789 - (51%)	Gaps:	125/789 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 LSLSLSPPLNRRRDMPALRGPFV-SLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGG 333
            :|::.....:..|..|..:.|.| ....|.......|.:.|:..:..|...||||||.:.||:||
  Rat    38 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPVPPEPEEEILGSDDEEQEDPADYCKGG 102

  Fly   334 YHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAI 398
            ||||.|||:|:.|:.|:||||||||||||||.|::.:::||:||||||.||.|||.|||:||:.:
  Rat   103 YHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCV 167

  Fly   399 RDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQV 463
            |::||.|..::.:|:|::.|.:.|:||:|.|:|||.||..|.|.|:|:|||||.:..|::|||||
  Rat   168 RESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQV 232

  Fly   464 LEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKS 528
            |:|||||||||.||||||||||||:.:|.|..  :::..|....:..|...|.....|...|.|
  Rat   233 LQGLDYLHSKCKIIHTDIKPENILMCVDGAYV--RRMAAEATEWQKAGAPPPSGSAVSTAPQQK- 294

  Fly   529 RAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLD--KEDTTTTTSSTLNSNTTSSLA 591
                    |.|..:.|............     |.::...|.  :|.........|..||||:.|
  Rat   295 --------PIGKISKNKKKKLKKKQKRQ-----AELLEKRLQEIEELEREAERKILEENTTSAEA 346

  Fly   592 SKYSSLLGDSECNGGLG-GSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPTD 655
            |...    |.||...:. ..|.:.:   |.::.|||.:|:.::..|.:...:::|     :...|
  Rat   347 SSEQ----DGECQPEVKLKEAELED---TTEEETAKDNGEVEDQEEKEDTEKENT-----EKDED 399

  Fly   656 LDPEPELDSKPNTVPEPSEGP-----------IPEQPTPNSTNSSCPSHNTATIAKSKINSNILS 709
             |.|.||:   |..|...|.|           :.||...:..:......|.......:.|:.
  Rat   400 -DVEQELE---NIDPTWMESPKANGHIENGLFLLEQQLEDEEDEEDDCANPEEYNLDEPNAE--- 457

  Fly   710 TCTSLTSTNEYCFTNTNTTTASTPSAPPSATPSSAPALASATPPSTCTPSFTQIAPSATAPATST 774
              :..|.::.|...|....... |.:|...||..:..|......|..:.......|..::|:...
  Rat   458 --SDYTYSSSYEQFNGELPNGQ-PKSPEFPTPLFSGPLEPVASDSVLSEGSPLTEPEESSPSRDR 519

  Fly   775 TCTTSAEFYDGDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNVHANAIPSQNQSQSSQNNTY 839
            :.|.||                      |:|.....|.|..|.|.|  |.:..||..:
  Rat   520 SRTVSA----------------------SSTGDLPKTKTRAADLLV--NPLDPQNADK------- 553

  Fly   840 TIQSLIDNSNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELA 904
                      :|||||||||||:.:.|||||||||||||||||:||.|:..||||||||:|||||
  Rat   554 ----------IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELA 608

  Fly   905 TGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQ-------------------SVIFR-------- 942
            ||||||:||:||.|||||||:|||:|||||||:                   ::|..
  Rat   609 TGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRK 673

  Fly   943 ----GKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSDFLLPMLEYNPVIRASA 1003
                ||:..::||..|.||:|||||||||.:||||||.|...:|.:|:|||:||||..|..||||
  Rat   674 YAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASA 738

  Fly  1004 AECLQHPWL 1012
            .|||:||||
  Rat   739 GECLRHPWL 747

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	STKc_SRPK	336..>504	CDD:271038	97/167 (58%)
		S_TKc	347..>492	CDD:214567	88/144 (61%)
		STKc_SRPK	<844..1012	CDD:271038	114/198 (58%)
Srpk2	XP_038963154.1	PKc_like	103..>291	CDD:419665	103/189 (54%)
		2A1904	<338..417	CDD:273344	25/94 (27%)
		PKc_like	<538..747	CDD:419665	120/227 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1290
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290680at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45924
orthoMCL	1	0.900	-	-		OOG6_100556
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.780