Protein Alignment Srpk79D and Srpk2

DIOPT Version :10

• Sequence 1: NP_001246881.1
• Gene: Srpk79D / 40461
• FlyBaseID: FBgn0025702
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_011248053.1
• Gene: Srpk2 / 20817
• MGIID: 1201408
• Length: 750
• Species: Mus musculus
• Alignment Length: 805
• Identity: 296/805 - (36%)
• Similarity: 407/805 - (50%)
• Gaps: 156/805 - (19%)

  Fly   270 LSLSLSPPLNRRRDMPALRGPFV-SLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGG 333
            :|::.....:..|..|..:.|.| ....|.......|...|:..:..|...||||||.:.||:||
Mouse    38 MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPAPPEPEEEILGSDDEEQEDPADYCKGG 102

  Fly   334 YHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAI 398
            ||||.|||:|:.|:.|:||||||||||||||.|::.:::||:||||||.||.|||.|||:||:.:
Mouse   103 YHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCV 167

  Fly   399 RDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQV 463
            |::||.|..::.:|:|::.|.:.|:||:|.|:|||.||..|.|.|:|:|||||.:..|::|||||
Mouse   168 RESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQV 232

  Fly   464 LEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSYISSIEKQTKS 528
            |:|||||||||.||||||||||||:.:|:|..  :::..|....:..|...|.....|...|.|
Mouse   233 LQGLDYLHSKCKIIHTDIKPENILMCVDDAYV--RRMAAEATEWQKAGAPPPSGSAVSTAPQQK- 294

  Fly   529 RAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLD--KEDTTTTTSSTLNSNTTSSLA 591
                    |.|..:.|............     |.::...|.  :|.........|..|.||:.|
Mouse   295 --------PIGKISKNKKKKLKKKQKRQ-----AELLEKRLQEIEELEREAERKILEENITSAEA 346

  Fly   592 SKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPTDL 656
            |      |:.:           :..|:.|  :|.|:: |.::..|.:|..:...:.
Mouse   347 S------GEQQ-----------DGEYQPE--VTLKAA-DLEDTTEEETAKDNGEVE--------- 382

  Fly   657 DPEPELDSKPNTVPEPSEGPIPEQPTPNSTNSSCPSHNTATIAKSKINSNILSTCTSL------T 715
            |.|.:.|::.... |..|..: ||...|.        :...:...|.|.:|.:...||      .
Mouse   383 DQEEKEDAEKENA-EKDEDDV-EQELANL--------DPTWVESPKANGHIENGPFSLEQQLEDE 437

  Fly   716 STNEYCFTNTNTTTASTPSAPPSATPSSAPALASATPPSTCTPSFTQIAPSATAPATSTTCTTSA 780
            ..:|....|........|:|....|.||               |:.|.               :.
Mouse   438 EDDEDDCANPEEYNLDEPNAESDYTYSS---------------SYEQF---------------NG 472

  Fly   781 EFYDGDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNVHANAIPSQNQSQSSQNNTYTIQS-- 843
            |..:|.|||:...|...|..:.         ..|...:....:.:..|.:|..|.:.:.|:.:
Mouse   473 ELPNGQHKTSEFPTPLFSGPLE---------PVACGSVISEGSPLTEQEESSPSHDRSRTVSASS 528

  Fly   844 -------------LIDN-------SNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYN 888
                         |:.|       ..:|||||||||||:.:.|||||||||||||||||:||.|:
Mouse   529 TGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYS 593

  Fly   889 YTADIWSTACLAFELATGDYLFDPHAGESYSRDEDHLAHIVELLGSIPQ---------------- 937
            ..||||||||:|||||||||||:||:||.|||||||:|||:|||||||:
Mouse   594 TPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRR 658

  Fly   938 ---SVIFR------------GKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSD 987
               ::|..            ||:..::||..|.||:|||||||||.:||||||.|...:|.:|:|
Mouse   659 DHIALIIELLGKVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTD 723

  Fly   988 FLLPMLEYNPVIRASAAECLQHPWL 1012
            ||:||||..|..||||.|||:||||
Mouse   724 FLIPMLEMVPEKRASAGECLRHPWL 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	Protein Kinases, catalytic domain	336..>504	CDD:473864	97/167 (58%)
		PHA03307	627..>759	CDD:223039	23/137 (17%)
		Protein Kinases, catalytic domain	<844..1012	CDD:473864	116/205 (57%)
Srpk2	XP_011248053.1	Protein Kinases, catalytic domain	103..>291	CDD:473864	103/189 (54%)
		2A1904	<338..418	CDD:273344	21/118 (18%)
		Protein Kinases, catalytic domain	<537..748	CDD:473864	116/210 (55%)