Protein Alignment Ddx1 and ddx1

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_001184253.1
• Gene: ddx1 / 556790
• ZFINID: ZDB-GENE-041001-215
• Length: 740
• Species: Danio rerio
• Alignment Length: 731
• Identity: 431/731 - (58%)
• Similarity: 550/731 - (75%)
• Gaps: 13/731 - (1%)

  Fly     1 MTAFEEFGVLPELGMATDELDWTLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVW 65
            |.||.|.||:||:..|.:|:||.||||:|||:||||||||||||||||||||||||.:|::|||:
Zfish     1 MAAFGEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVY 65

  Fly    66 ETLRDLEEGKAGKGGA-IGGAV-TPWTMSFFDRGNALAVTPDGLRCQSREFKEWHGCRATTGVRG 128
            ||::||:|||.|:... .|||| :.|.|:.|||..|.|:..|||.|||||||||||||.|..|.
Zfish    66 ETIKDLQEGKKGRSAVKTGGAVFSKWQMNPFDRSTAFAIGSDGLCCQSREFKEWHGCRTTKAVT- 129

  Fly   129 KGKFYFEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGC 193
            ||::|:|....|:|||||||||.||:|||||.:.|||||||||||:|:|||.|||.|...|.|||
Zfish   130 KGRYYYEVACHDQGLCRVGWSTAQASLDLGTDKYGFGFGGTGKKSHNKQFDSYGEEFTMHDTIGC 194

  Fly   194 LLDLKNQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGAC 258
            .:||:...|||:|||.:||:||.:|..|..:.|:.:.||||||::||||...||:.|.:|:|...
Zfish   195 YIDLEKGHVSFSKNGNDLGLAFEIPQQLRSQPFFASCVLKNAELKFNFGDEAFKHQPKDGYVALN 259

  Fly   259 QAGPEHSKANPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLL 323
            ||...|...:..|| :|.....|.:.|||:|:|:|||:||||||.|.:.:||.::.||::|.||:
Zfish   260 QAPEGHVVKSSQTG-SAKVTQVKSSSNAPRALIIEPSKELAEQTLNNVNQFKKYVDNPKLRELLI 323

  Fly   324 IGGVRLEEQKAQLMQGTHIVVGTPGRLEEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLH 388
            ||||..:||...|..|..|||||||||:::|::|.:.|:..||.||||.|.||..|.|:.|.|::
Zfish   324 IGGVAAKEQLNVLESGVDIVVGTPGRLDDLISTGKLDLSQVRFLVLDECDGLLSAGNTDFIMRIY 388

  Fly   389 KQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMD 453
            .|||::||||:|||::|||||||:|:|||::|::|||||||||||||:|||||||||..|:|:.|
Zfish   389 NQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPETVHHVVVTVNPKND 453

  Fly   454 TTWQSL-RQPIGTDGVHDRDNVHPGNHSKETLSQAVKLLKGEYCVHAIDKHNMDRAIIFCRTKQD 517
            ..|:.| :..|.||.||.:|:..||.:|.|..|:|:|:|||||.|.||.:|.||:||||||||.|
Zfish   454 KLWERLGKNHIRTDEVHAKDDTRPGANSPEMWSEAIKILKGEYTVRAIKEHKMDQAIIFCRTKID 518

  Fly   518 CDNLER-FLRQRG-----GKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTDVAARGLDITG 576
            |||:|: |::|.|     |..:|||||||||||.|||.|||.||:|:|||||||||||||:|:.|
Zfish   519 CDNMEQYFIKQGGGPDKKGHQFSCVCLHGDRKPNERKYNLERFKKQEVKFLICTDVAARGIDVRG 583

  Fly   577 LPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLVATVPEKVWYHGEWCKSRGRSCNNTNLTEV 641
            :|::|||||||:|.||||||||||||:||||||||||...||||||  .|.|||:.|.||.|.|.
Zfish   584 VPYVINVTLPDEKENYVHRIGRVGRADRMGLAISLVAMEKEKVWYH--VCASRGKGCYNTRLKEN 646

  Fly   642 RGCCIWYNEPNLLAEVEDHLNITIQQVDKTMDVPVNDFDGKVVYGQKNLRTGSGYEDHVEQLVPT 706
            .||.|||||..||:::|:||..||.|.:..:.|||::|||||.|||:....|..|:.||:.|.||
Zfish   647 GGCTIWYNEKELLSDIEEHLKCTITQCEPDIKVPVDEFDGKVTYGQRRATGGGLYKGHVDILAPT 711

  Fly   707 VRKLTELELQSQSLFL 722
            |::|..||.::|:.||
Zfish   712 VQELANLEREAQTSFL 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120	49/68 (72%)
		SPRY_DDX1	91..242	CDD:293933	91/150 (61%)
		SrmB	283..613	CDD:440279	209/336 (62%)
ddx1	NP_001184253.1	DEAD-like_helicase_N	4..>62	CDD:475120	42/57 (74%)
		SPRY_DDX1	93..245	CDD:293933	93/152 (61%)
		SrmB	263..698	CDD:440279	257/437 (59%)