Protein Alignment Ddx1 and Rm62

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 157/596 - (26%)
• Similarity: 227/596 - (38%)
• Gaps: 167/596 - (28%)

  Fly    69 RDL-EEGKAGKGGAIGGAVTPWTMSFFDR------GNALAVTPDGLRCQSREFKEWHGCRATTGV 126
            ||. ..|:.|:||..||.         ||      ||.......|        .::||.|
  Fly   150 RDFGHSGRGGRGGDRGGD---------DRRGGGGGGNRFGGGGGG--------GDYHGIR----- 192

  Fly   127 RGKGKFYFEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVI 191
              .|:  .|....|.|               |..|.| |.||.|.:..       |...|..|:.
  Fly   193 --NGR--VEKRRDDRG---------------GGNRFG-GGGGFGDRRG-------GGGGGSQDLP 230

  Fly   192 GCLLDLKN--------------------QEVSFTKNGQNLGVAFRLPDNLA--KETFYPAVVLKN 234
            ...:|..|                    .||...:..|.:.|..::|:.:.  .|...|..|:|.
  Fly   231 MRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQRYREEQEITVRGQVPNPIQDFSEVHLPDYVMKE 295

  Fly   235 AEMQFNFGKTDFKYAP-------------GNGFVGACQAGPEHSKANPITGPAAG--APSAKPAP 284
            ...|      .:| ||             |:.|||..:.|         :|...|  .|:.....
  Fly   296 IRRQ------GYK-APTAIQAQGWPIAMSGSNFVGIAKTG---------SGKTLGYILPAIVHIN 344

  Fly   285 N--------APQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTH 341
            |        .|.|:::.|:||||:|......:|.   |:..||:..:.||.....|...|.:|..
  Fly   345 NQQPLQRGDGPIALVLAPTRELAQQIQQVATEFG---SSSYVRNTCVFGGAPKGGQMRDLQRGCE 406

  Fly   342 IVVGTPGRLEEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPKITSDGR-RLQMVV 405
            ||:.|||||.:.:::|...|..|.:.||||||.:|..|:       ..||.||.|..| ..|.::
  Fly   407 IVIATPGRLIDFLSAGSTNLKRCTYLVLDEADRMLDMGF-------EPQIRKIVSQIRPDRQTLM 464

  Fly   406 CSATLHAFEVKKMAERLMHFPTWVDLKG-EDAVPETVHHVVCLVDPQMDTTWQSLRQPIGTDGVH 469
            .|||... |||::||..:.....:::.. |.:....:..||.:.|
  Fly   465 WSATWPK-EVKQLAEDFLGNYIQINIGSLELSANHNIRQVVDVCD-------------------- 508

  Fly   470 DRDNVHPGNHSKETLSQAVKLLKGEYCVHAIDKHNMDRAIIFCRTKQDCDNLERFLRQRGGKHYS 534
                    ..|||  .:...||...|..    ..:..:.|||..||:..|||.||:|..|.:
  Fly   509 --------EFSKE--EKLKTLLSDIYDT----SESPGKIIIFVETKRRVDNLVRFIRSFGVR--- 556

  Fly   535 CVCLHGDRKPQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRV 599
            |..:|||:...||...|..|:..:...|:.|||||||||:.|:.::||...|.:..:|:|||||.
  Fly   557 CGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRT 621

  Fly   600 GRAERMGLAIS 610
            ||:...|.:.:
  Fly   622 GRSNTKGTSFA 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120	2/4 (50%)
		SPRY_DDX1	91..242	CDD:293933	34/178 (19%)
		SrmB	283..613	CDD:440279	104/338 (31%)
Rm62	NP_524243.2	DEAD-like_helicase_N	231..669	CDD:475120	127/466 (27%)