Protein Alignment Ddx1 and pths

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_610090.1
• Gene: pths / 35379
• FlyBaseID: FBgn0032919
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 618
• Identity: 127/618 - (20%)
• Similarity: 198/618 - (32%)
• Gaps: 283/618 - (45%)

  Fly     4 FEEFGVLPELGMATDELDWTLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVWETL 68
            :::.|:...|..|.|||.|..|:.:|.||||:.|.|.||:..|||||||||||.||||.
  Fly    63 WKDLGLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILH------ 121

  Fly    69 RDLEEGKAGKGGAIGGAVTPWTMSFFDRGNALAVTPDGLRCQSREFKEWHGCRATTGVRGKGKFY 133
                                                                             
  Fly   122 ----------------------------------------------------------------- 121

  Fly   134 FEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGCLLDLK 198
                                                                             
  Fly   122 ----------------------------------------------------------------- 121

  Fly   199 NQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQAGPE 263
                                           .:|:|.:..|
  Fly   122 -------------------------------ALLENPQRYF------------------------ 131

  Fly   264 HSKANPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVR 328
                                     |:::.|:||||.|...|.|...   |...::..:::||:.
  Fly   132 -------------------------ALVLTPTRELAFQIGEQFEALG---SGIGIKCCVVVGGMD 168

  Fly   329 LEEQKAQLMQGTHIVVGTPGRL-EEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIP 392
            :..|..||.:..||::.||||| :.:.|.....|...::.|:||||.:|...:...:|::.|.:|
  Fly   169 MVAQGLQLAKKPHIIIATPGRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVLP 233

  Fly   393 KITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMDTTWQ 457
                  |..:..:.|||: ..:|||:....:..|..|::..:                     :|
  Fly   234 ------RERRTFLFSATM-TKKVKKLQRASLKDPVKVEVSNK---------------------YQ 270

  Fly   458 SLRQPIGTDGVHDRDNVHPGNHSKETLSQAVKLL----KGEYCVHAIDKHNMDRAIIFCRTKQDC 518
            ::.|                      |.|:...:    |..|.||.:::...:..:|||.|   |
  Fly   271 TVEQ----------------------LQQSYLFIPVKYKDVYLVHILNELAGNSFMIFCST---C 310

  Fly   519 DNLER---FLRQRGGKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFM 580
            :|..:   .||..|   .:.:.|||.....:|...|..||.:....||.||||:|||||..:..:
  Fly   311 NNTVKTALMLRALG---LAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVV 372

  Fly   581 INVTLPDDKTNYVHRIGRVGRAERMGLAISLVA 613
            :|..:|....:|:||:||..||.|.|.||:||:
  Fly   373 VNFDIPTHSKDYIHRVGRTARAGRSGKAITLVS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120	32/68 (47%)
		SPRY_DDX1	91..242	CDD:293933	3/150 (2%)
		SrmB	283..613	CDD:440279	91/337 (27%)
pths	NP_610090.1	SrmB	62..480	CDD:440279	127/618 (21%)