Protein Alignment Ddx1 and Ddx56

DIOPT Version :10

• Sequence 1: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: NP_523434.2
• Gene: Ddx56 / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 655
• Identity: 124/655 - (18%)
• Similarity: 190/655 - (29%)
• Gaps: 310/655 - (47%)

  Fly     4 FEEFGVLPELGMATDELDWTLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVWETL 68
            |.|..:...:..|..:|.|..||.:|:.||||:|.|.||::.|.||||||..:.||::|
  Fly    11 FHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQ------ 69

  Fly    69 RDLEEGKAGKGGAIGGAVTPWTMSFFDRGNALAVTPDGLRCQSREFKEWHGCRATTGVRGKGKFY 133
                                                                             
  Fly    70 ----------------------------------------------------------------- 69

  Fly   134 FEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGCLLDLK 198
                                                                   .::...|:..
  Fly    70 -------------------------------------------------------KILNSKLNAS 79

  Fly   199 NQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQAGPE 263
            .|.||
  Fly    80 EQYVS------------------------------------------------------------ 84

  Fly   264 HSKANPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVR 328
                                     |:::.|::||..|:...||:.        |.|...:  ||
  Fly    85 -------------------------AVVLAPTKELCRQSRKVIEQL--------VESCGKV--VR 114

  Fly   329 LEE----------QKAQLMQGTHIVVGTPGRLEEMINSGLVL-LTHCRFFVLDEADALLKQGYTE 382
            :.:          |:..|.:...|||.||..|.....:|.|: |.|....|:||||.:...||.:
  Fly   115 VADIADSSNDTVTQRHALSESPDIVVATPANLLAYAEAGSVVDLKHVETLVVDEADLVFAYGYEK 179

  Fly   383 LIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCL 447
            ...||.|.:|.|      .|.|:.|||| ..:|.:|....::.|  |.||.|:  ||.|
  Fly   180 DFKRLIKHLPPI------YQAVLVSATL-TDDVVRMKGLCLNNP--VTLKLEE--PELV------ 227

  Fly   448 VDPQMDTTWQSLRQPIGTDGVHDRDNVHPGNHSKETLSQA---VKLLKGEYCVHAIDKHNMDRAI 509
              ||...:             |.|  :....:.|..:..|   ::|::|             ::|
  Fly   228 --PQDQLS-------------HQR--ILAEENDKPAILYALLKLRLIRG-------------KSI 262

  Fly   510 IFCRTKQDCDNLERFLRQRGGKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTD-------- 566
            ||..:...|..:..||.|.|.:  :|| |:.:.....|...:..|.:.....:|.:|
  Fly   263 IFVNSIDRCYKVRLFLEQFGIR--ACV-LNSELPANIRIHTISQFNKGTYDIIIASDEHHMEKPG 324

  Fly   567 -----------------VAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLVAT 614
                             .|:||:|...:..:||...|.|.|:|:||.||..|....|..:|.|:.
  Fly   325 GKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSM 389

  Fly   615 VPEKV 619
            ...||
  Fly   390 KESKV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120	26/68 (38%)
		SPRY_DDX1	91..242	CDD:293933	4/150 (3%)
		SrmB	283..613	CDD:440279	91/368 (25%)
Ddx56	NP_523434.2	DEADc_DDX56	16..221	CDD:350719	74/434 (17%)
		SF2_C_DEAD	232..387	CDD:350174	38/185 (21%)